Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4819350 | 1.00 | PDGFRB (0.47) | PDGFRBPDGFRACYP1A2RAB9AKDM1A | |
| SCHEMBL4814522 | 0.84 | PDGFRB (0.45) | PDGFRBPDGFRACYP1A2RAB9AKDM1A | |
| SCHEMBL27579596 | 0.83 | PDGFRB (0.47) | PDGFRBPDGFRACYP1A2RAB9AKDM1A | |
| SCHEMBL27513241 | 0.83 | PDGFRB (0.47) | PDGFRBPDGFRACYP1A2RAB9AKDM1A | |
| SCHEMBL27514595 | 0.83 | PDGFRB (0.47) | PDGFRBPDGFRACYP1A2RAB9AKDM1A | |
| SCHEMBL28751294 | 0.83 | PDGFRB (0.47) | PDGFRBPDGFRACYP1A2RAB9AKDM1A | |
| SCHEMBL4815367 | 0.83 | PDGFRB (0.50) | PDGFRBPDGFRACYP1A2RAB9AKDM1A | |
| SCHEMBL273345 | 0.81 | PDGFRB (0.51) | PDGFRBPDGFRACYP1A2RAB9AKDM1A | |
| SCHEMBL4815350 | 0.79 | PDGFRB (0.50) | PDGFRBPDGFRACYP1A2RAB9AKDM1A | |
| SCHEMBL28879834 | 0.79 | PDGFRB (0.50) | PDGFRBPDGFRACYP1A2RAB9AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39836-E1 | Macrolide antinfective agents | KOSAN BIOSCIENCES, INC. (US) | 2007-09-11 | — | — | US | claimed |
| US-6593302-B2 | Antibiotics | KOSAN BIOSCIENCES, INC. | 2003-07-15 | — | — | US | claimed |