Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4819797 | 0.86 | PDGFRB (0.47) | PDGFRBPDGFRACYP1A2RAB9AKDM1A | |
| SCHEMBL273345 | 0.84 | PDGFRB (0.51) | PDGFRBPDGFRACYP1A2RAB9AKDM1A | |
| SCHEMBL4819350 | 0.83 | PDGFRB (0.47) | PDGFRBPDGFRACYP1A2RAB9AKDM1A | |
| SCHEMBL5508798 | 0.83 | PDGFRB (0.47) | PDGFRBPDGFRACYP1A2RAB9AKDM1A | |
| SCHEMBL3396692 | 0.83 | CYP1A2 (0.55) | PDGFRBPDGFRACYP1A2RAB9AKDM1A | |
| SCHEMBL28879834 | 0.82 | PDGFRB (0.50) | PDGFRBPDGFRACYP1A2RAB9AKDM1A | |
| SCHEMBL4815350 | 0.82 | PDGFRB (0.50) | PDGFRBPDGFRACYP1A2RAB9AKDM1A | |
| SCHEMBL16612703 | 0.81 | PDGFRB (0.46) | PDGFRBPDGFRACYP1A2RAB9AKDM1A | |
| SCHEMBL4817698 | 0.80 | CYP1A2 (0.48) | PDGFRBPDGFRACYP1A2RAB9AKDM1A | |
| SCHEMBL3820110 | 0.79 | CYP1A2 (0.52) | PDGFRBPDGFRACYP1A2RAB9AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247277-B1 | PROCESS FOR THE PREPARATION OF 5-ALKYLQUINOLINIC ACIDS AND MEANS FOR CARRYING OUT THIS PROCESS | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1991-09-11 | — | — | EP | claimed |
| CN-103539734-A | Preparation method of 3-allyl quinoline | UNIV SHANGHAI JIAOTONG | 2014-01-29 | — | — | CN | disclosed |
| CN-103539734-A | Preparation method of 3-allyl quinoline | UNIV SHANGHAI JIAOTONG | 2014-01-29 | — | — | CN | disclosed |
| CN-102766089-A | 3-(3-quinolyl)-2-propenyl-1-halide and its preparation method | SHANGHAI INST PHARM INDUSTRY | 2012-11-07 | — | — | CN | disclosed |
| US-20100247938-A1 | MATERIAL FOR THREE-DIMENSIONAL MODELING, PROCESS FOR PRODUCING THREE-DIMENSIONAL MODEL, AND THREE-DIMENSIONAL MODEL | FUJIFILM CORPORATION (JP) | 2010-09-30 | — | — | US | disclosed |
| US-20100247938-A1 | MATERIAL FOR THREE-DIMENSIONAL MODELING, PROCESS FOR PRODUCING THREE-DIMENSIONAL MODEL, AND THREE-DIMENSIONAL MODEL | FUJIFILM CORPORATION (JP) | 2010-09-30 | — | — | US | disclosed |
| US-7365174-B2 | Azalide and azalactam derivatives and method for producing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2008-04-29 | — | — | US | disclosed |
| US-RE39836-E1 | Macrolide antinfective agents | KOSAN BIOSCIENCES, INC. (US) | 2007-09-11 | — | — | US | disclosed |
| US-20070042974-A1 | Nozel azalide and azalactam derivatives and method for producing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1661904-A1 | NOVEL AZALIDE AND AZALACTAM DERIVATIVES AND PROCESS FOR THE PRODUCTION OF THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 2006-05-31 | — | — | EP | disclosed |
| US-6593302-B2 | Antibiotics | KOSAN BIOSCIENCES, INC. | 2003-07-15 | — | — | US | disclosed |
| US-20020119938-A1 | Macrolide antiinfective agents | CHU DANIEL (US) | 2002-08-29 | — | — | US | disclosed |
| US-6395710-B1 | CONTROLLING INFECTIONS | KOSAN BIOSCIENCES, INC. | 2002-05-28 | — | — | US | disclosed |
| EP-1171446-A2 | MACROLIDE ANTIINFECTIVE AGENTS | Kosan Biosciences, Inc. (US) | 2002-01-16 | — | — | EP | disclosed |
| EP-0847389-A4 | PROCESS FOR PREPARING QUINOLINE BASES | REILLY IND INC (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-2000063224-A2 | MACROLIDE ANTIINFECTIVE AGENTS | KOSAN BIOSCIENCES, INC. (US) | 2000-10-26 | — | — | WO | disclosed |
| EP-0847389-A1 | PROCESS FOR PREPARING QUINOLINE BASES | REILLY INDUSTRIES, INC. (US) | 1998-06-17 | — | — | EP | disclosed |
| US-5700942-A | Process for preparing quinoline bases | REILLY INDUSTRIES, INC. (US) | 1997-12-23 | — | — | US | disclosed |
| WO-1997003051-A1 | PROCESS FOR PREPARING QUINOLINE BASES | REILLY INDUSTRIES, INC. (US) | 1997-01-30 | — | — | WO | disclosed |
| EP-0247277-A2 | Process for the preparation of 5-alkylquinolinic acids and means for carrying out this process | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1987-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020119938-A1 | Macrolide antiinfective agents | MLNR, DOHH, NOP2 | PDGFRB 2778/4885PDGFRA 3142/4885CYP1A2 2938/4885 |
| US-20070042974-A1 | Nozel azalide and azalactam derivatives and method for producing the same | BCL6, NR4A1, NR4A2 | PDGFRB 2207/4885PDGFRA 2360/4885CYP1A2 583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.