Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2562392 | 0.87 | POLB (0.51) | POLBTSHRMEN1KMT2ATRPM8 | |
| SCHEMBL2726847 | 0.86 | TSHR (0.70) | POLBTSHRMEN1KMT2ATHRB | |
| SCHEMBL666126 | 0.86 | OPRM1 (0.53) | POLBTSHRMEN1KMT2ATHRB | |
| SCHEMBL5511513 | 0.86 | POLB (0.57) | POLBTSHRMEN1KMT2ATRPM8 | |
| SCHEMBL30528370 | 0.86 | POLB (0.50) | POLBTSHRMEN1KMT2ATRPM8 | |
| SCHEMBL15059410 | 0.86 | POLB (0.50) | POLBTSHRMEN1KMT2ATRPM8 | |
| SCHEMBL23355845 | 0.84 | MEN1 (0.51) | POLBTSHRMEN1KMT2ATRPM8 | |
| SCHEMBL5141980 | 0.84 | MEN1 (0.51) | POLBTSHRMEN1KMT2ATRPM8 | |
| SCHEMBL4162403 | 0.83 | MEN1 (0.50) | POLBTSHRMEN1KMT2ATRPM8 | |
| SCHEMBL18378463 | 0.83 | TSHR (0.48) | POLBTSHRMEN1KMT2ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378836-A | Antibody inhibitors, fungicides; antiinflammatory and antitumor agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-01-03 | — | — | US | claimed |
| CN-110621678-A | Antitumor compounds | 法马马有限公司 | 2019-12-27 | — | — | CN | disclosed |
| US-9434719-B2 | 3-pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH | NOVARTIS AG (CH) | 2016-09-06 | — | — | US | disclosed |
| EP-2854527-A1 | STORAGE AIDS COMPRISING PLANT PROTECTANTS AND THEIR USE | se ma Gesellschaft für Innovationen mbH (DE) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013175461-A1 | STORAGE AIDS COMPRISING PLANT PROTECTANTS AND THEIR USE | se ma Gesellschaft für Innovationen mbH (DE) | 2013-11-28 | — | — | WO | disclosed |
| EP-1470258-B1 | COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS | TFL LEDERTECHNIK GMBH (DE) | 2013-08-28 | — | — | EP | disclosed |
| WO-2012006276-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH ARYL CARBAMATES | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-01-12 | — | — | WO | disclosed |
| US-7250456-B2 | Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials | TFL LEDERTECHNIK GMBH (DE) | 2007-07-31 | — | — | US | disclosed |
| US-6967196-B1 | Sulfonamide compounds and uses thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-22 | — | — | US | disclosed |
| US-20050148702-A1 | Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials | TFL LEDERTECHNIK GMBH (DE) | 2005-07-07 | — | — | US | disclosed |
| EP-1470258-A1 | COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS | TFL Ledertechnik GmbH (DE) | 2004-10-27 | — | — | EP | disclosed |
| CN-1478077-A | Benzamide compounds as APO B secretion inhibitors | ����ҩƷ��ҵ��ʽ���� | 2004-02-25 | — | — | CN | disclosed |
| WO-2003064707-A1 | COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS | TFL LEDERTECHNIK GMBH (DE) | 2003-08-07 | — | — | WO | disclosed |
| CN-1307565-A | Quinolones used as MRS inhibitor and bactericides | SMITHKLINE BEECHAM PLC (GB) | 2001-08-08 | — | — | CN | disclosed |
| CN-1036591-C | Carbamates of rapamycin | AMERICAN HOME PROD (US) | 1997-12-03 | — | — | CN | disclosed |
| US-5378836-A | Antibody inhibitors, fungicides; antiinflammatory and antitumor agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-01-03 | — | — | US | disclosed |