Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 12/20 | 0.45 |
| ▸ | AR | P10275 | 6/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5507815 | 0.96 | VDR (0.45) | VDRARGRIN2DGRIN2AGRIN2B | |
| SCHEMBL5505759 | 0.94 | VDR (0.44) | VDRARGRIN2DGRIN2AGRIN2B | |
| SCHEMBL5499834 | 0.92 | VDR (0.44) | VDRAR | |
| SCHEMBL6263044 | 0.89 | VDR (0.49) | VDRAR | |
| SCHEMBL1780645 | 0.88 | VDR (0.43) | VDRAR | |
| SCHEMBL5503318 | 0.88 | VDR (0.44) | VDRAR | |
| SCHEMBL6225868 | 0.88 | VDR (0.47) | VDRAR | |
| SCHEMBL5503357 | 0.87 | VDR (0.43) | VDRAR | |
| SCHEMBL5504678 | 0.86 | VDR (0.41) | VDRAR | |
| SCHEMBL5500473 | 0.85 | VDR (0.40) | VDRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836151-A2 | VITAMIN D RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006069153-A2 | VITAMIN D RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-06-29 | — | — | WO | disclosed |