Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 2/20 | 0.62 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.62 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.62 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.62 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.62 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.62 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.62 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.62 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.62 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.62 |
| ▸ | ARG1 | P05089 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8296914 | 1.00 | GRIN2D (0.62) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8301662 | 1.00 | GRIN2D (0.62) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8296912 | 1.00 | GRIN2D (0.62) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL27668252 | 1.00 | GRIN2D (0.62) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL15610738 | 0.85 | ARG1 (0.66) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1241267 | 0.85 | ARG1 (0.66) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL4864129 | 0.85 | GRIN2D (0.49) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6436339 | 0.84 | ARG1 (0.59) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6436342 | 0.84 | ARG1 (0.59) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6436335 | 0.84 | ARG1 (0.59) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199105-B2 | Lincomycin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS, INC. (US) | 2007-04-03 | — | — | US | claimed |
| CN-100404543-C | Intermediate of synthesized pirilmycin, preparation method and usage | ZHEJIANG HISUN PHARMACEUTICAL (CN) | 2008-07-23 | — | — | CN | disclosed |
| US-7199105-B2 | Lincomycin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS, INC. (US) | 2007-04-03 | — | — | US | disclosed |
| CN-1916011-A | Intermediate of synthesized pirilmycin, preparation method and usage | HIAZHENG PHARMACEUTICAL IND CO (CN) | 2007-02-21 | — | — | CN | disclosed |
| US-7164011-B2 | Lincomycin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS, INC. (US) | 2007-01-16 | — | — | US | disclosed |
| EP-1654268-A2 | LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2006-05-10 | — | — | EP | disclosed |
| CN-1681832-A | Lincomycin derivatives possessing antibacterial activity | VICURON PHARM INC (US) | 2005-10-12 | — | — | CN | disclosed |
| WO-2005007665-A2 | LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2005-01-27 | — | — | WO | disclosed |
| EP-0614986-B1 | Enzymatic racemate cleavage of 2-pipéridine alkylcarboxylates | SYNTHELABO (FR) | 1999-07-21 | — | — | EP | disclosed |
| CN-1131153-A | 1-oxy-2-(phenylsulfonamido-) amyl piperidine derivant, its preparation method and medicinal use thereof | SYNTHELABO (FR) | 1996-09-18 | — | — | CN | disclosed |
| EP-0353248-B1 | METHOD FOR RESOLUTION OF STEREOISOMERS IN MULTIPHASE AND EXTRACTIVE MEMBRANE REACTORS | SEPRACOR INC (US) | 1995-03-29 | — | — | EP | disclosed |
| US-5391556-A | Thrombin inhibitors | KARL THOMAE GMBH (DE) | 1995-02-21 | — | — | US | disclosed |
| EP-0614986-A1 | Enzymatic racemate cleavage of 2-pipéridine alkylcarboxylates and their use as synthesis intermediates | SYNTHELABO (FR) | 1994-09-14 | — | — | EP | disclosed |
| EP-0353248-A4 | METHOD FOR RESOLUTION OF STEREOISOMERS IN MULTIPHASE AND EXTRACTIVE MEMBRANE REACTORS | — | 1991-07-17 | — | — | EP | disclosed |
| EP-0353248-A1 | METHOD FOR RESOLUTION OF STEREOISOMERS IN MULTIPHASE AND EXTRACTIVE MEMBRANE REACTORS. | SEPRACOR INC (US) | 1990-02-07 | — | — | EP | disclosed |
| US-4800162-A | ENZYME-ACTIVATED MEMBRANE | SEPRACOR, INC. (US) | 1989-01-24 | — | — | US | disclosed |
| WO-1988007582-A1 | METHOD FOR RESOLUTION OF STEREOISOMERS IN MULTIPHASE AND EXTRACTIVE MEMBRANE REACTORS | SEPRACOR, INC. (US) | 1988-10-06 | — | — | WO | disclosed |