Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.31 |
| ▸ | MTOR | P42345 | 2/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509457 | 0.92 | F10 (0.37) | F10NPC1RAB9AKMT2AHTT | |
| SCHEMBL5506699 | 0.92 | F10 (0.38) | F10NPC1RAB9AKMT2AHTT | |
| SCHEMBL5502514 | 0.92 | FAAH (0.39) | F10NPC1RAB9AKMT2AHTT | |
| SCHEMBL5502455 | 0.91 | F10 (0.42) | F10FAAHTRPV1 | |
| SCHEMBL5503069 | 0.91 | F10 (0.46) | F10NPC1RAB9AKMT2AHTT | |
| SCHEMBL5503849 | 0.90 | F10 (0.40) | F10MAPTFAAHTRPV1 | |
| SCHEMBL4465281 | 0.88 | F10 (0.45) | F10NPC1RAB9AKMT2AHTT | |
| SCHEMBL5509717 | 0.85 | F10 (0.43) | F10FAAHTRPV1 | |
| SCHEMBL5505128 | 0.85 | F10 (0.48) | F10NPC1RAB9AKMT2AHTT | |
| SCHEMBL5512752 | 0.84 | FAAH (0.38) | F10FAAHTRPV1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747217-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005111029-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |