SCHEMBL5509944

SCHEMBL5509944

CCCCCCCCCN1CCCCC1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
KCNH2 Q12809 1/20 0.49
POLB P06746 1/20 0.49
TSHR P16473 1/20 0.49
S1PR1 P21453 3/20 0.48
S1PR3 Q99500 3/20 0.48
S1PR5 Q9H228 3/20 0.48
S1PR4 O95977 1/20 0.47
NR1I2 O75469 1/20 0.45
KCNK3 O14649 1/20 0.43
LMNA P02545 1/20 0.43
SLC6A1 P30531 1/20 0.43
BCHE P06276 3/20 0.42
OPRD1 P41143 1/20 0.41
GBA1 P04062 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20210387 1.00 SMN1; SMN2 (0.49) SMN1; SMN2CYP3A4CYP2D6KCNH2POLB
SCHEMBL10623312 1.00 SMN1; SMN2 (0.49) SMN1; SMN2CYP3A4CYP2D6KCNH2POLB
SCHEMBL7114915 0.98 SMN1; SMN2 (0.50) SMN1; SMN2CYP3A4CYP2D6KCNH2POLB
SCHEMBL4947692 0.98 SMN1; SMN2 (0.50) SMN1; SMN2CYP3A4CYP2D6KCNH2POLB
SCHEMBL7114016 0.98 SMN1; SMN2 (0.50) SMN1; SMN2CYP3A4CYP2D6KCNH2POLB
SCHEMBL8674297 0.95 S1PR1 (0.51) SMN1; SMN2CYP3A4CYP2D6KCNH2POLB
SCHEMBL5513172 0.95 S1PR1 (0.51) SMN1; SMN2CYP3A4CYP2D6KCNH2POLB
SCHEMBL20442187 0.95 S1PR1 (0.51) SMN1; SMN2CYP3A4CYP2D6KCNH2POLB
SCHEMBL9150671 0.95 S1PR1 (0.51) SMN1; SMN2CYP3A4CYP2D6KCNH2POLB
SCHEMBL9150667 0.95 S1PR1 (0.51) SMN1; SMN2CYP3A4CYP2D6KCNH2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed