Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7114915 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP3A4CYP2D6KCNH2POLB | |
| SCHEMBL7114016 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP3A4CYP2D6KCNH2POLB | |
| SCHEMBL5509944 | 0.98 | SMN1; SMN2 (0.49) | SMN1; SMN2CYP3A4CYP2D6KCNH2POLB | |
| SCHEMBL20210387 | 0.98 | SMN1; SMN2 (0.49) | SMN1; SMN2CYP3A4CYP2D6KCNH2POLB | |
| SCHEMBL10623312 | 0.98 | SMN1; SMN2 (0.49) | SMN1; SMN2CYP3A4CYP2D6KCNH2POLB | |
| SCHEMBL3442998 | 0.95 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP3A4CYP2D6KCNH2POLB | |
| SCHEMBL13975748 | 0.95 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP3A4CYP2D6KCNH2POLB | |
| SCHEMBL9093440 | 0.95 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP3A4CYP2D6KCNH2POLB | |
| SCHEMBL1381895 | 0.95 | NR1I2 (0.50) | SMN1; SMN2CYP3A4CYP2D6KCNH2POLB | |
| SCHEMBL1381896 | 0.95 | NR1I2 (0.50) | SMN1; SMN2CYP3A4CYP2D6KCNH2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784603-B1 | RACEMISATION OF PRECURSORS TO LEVOBUPIVACAINE AND ANALOGUES THEREOF | DARWIN DISCOVERY LTD (GB) | 2003-04-23 | — | — | EP | claimed |
| US-6156900-A | Racemization of precursors to levobupivacaine and analogues thereof | DARWIN DISCOVERY LIMITED (GB) | 2000-12-05 | — | — | US | claimed |
| EP-0723586-B1 | ENZYME AND ITS USE IN PREPARING (S)-PIPECOLIC ACID | DARWIN DISCOVERY LTD (GB) | 1999-12-22 | — | — | EP | claimed |
| US-5733754-A | ACYLASE WHICH HYDROLYZING N-ACETYLPIPECOLIC ACID | CHIROSCIENCE LIMITED (GB) | 1998-03-31 | — | — | US | claimed |
| EP-0784603-A2 | RACEMISATION OF PRECURSORS TO LEVOBUPIVACAINE AND ANALOGUES THEREOF | Chiroscience Limited (GB) | 1997-07-23 | — | — | EP | claimed |
| EP-0723586-A1 | ENZYME AND ITS USE IN PREPARING (S)-PIPECOLIC ACID | Chiroscience Limited (GB) | 1996-07-31 | — | — | EP | claimed |
| WO-1996011173-A2 | RACEMISATION OF PRECURSORS TO LEVOBUPIVACAINE AND ANALOGUES THEREOF | CHIROSCIENCE LIMITED (GB) | 1996-04-18 | — | — | WO | claimed |
| WO-1995010604-A1 | ENZYME AND ITS USE IN PREPARING (S)-PIPECOLIC ACID | CHIROSCIENCE LIMITED (GB) | 1995-04-20 | — | — | WO | claimed |
| US-11987590-B2 | Compounds that participate in cooperative binding and uses thereof | Revolution Medicines, Inc. (US) | 2024-05-21 | — | — | US | disclosed |
| WO-2024102421-A2 | COMPOUNDS, COMPLEXES, AND METHODS FOR THEIR PREPARATION AND OF THEIR USE | Revolution Medicines, Inc. (US) | 2024-05-16 | — | — | WO | disclosed |
| EP-4289950-A2 | MACROCYCLIC COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND MEDICAL USES THEREOF | Revolution Medicines, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| EP-4242304-A2 | METHODS AND REAGENTS FOR ANALYZING PROTEIN-PROTEIN INTERFACES | Warp Drive Bio, Inc. (US) | 2023-09-13 | — | — | EP | disclosed |
| EP-3247378-B1 | MACROCYCLIC COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND MEDICAL USES THEREOF | WARP DRIVE BIO INC (US) | 2023-07-19 | — | — | EP | disclosed |
| US-20220144849-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2022-05-12 | — | — | US | disclosed |
| EP-0784603-A2 | RACEMISATION OF PRECURSORS TO LEVOBUPIVACAINE AND ANALOGUES THEREOF | Chiroscience Limited (GB) | 1997-07-23 | — | — | EP | disclosed |
| EP-0723586-A1 | ENZYME AND ITS USE IN PREPARING (S)-PIPECOLIC ACID | Chiroscience Limited (GB) | 1996-07-31 | — | — | EP | disclosed |
| EP-0719779-A1 | SUBSTITUTED THIAZOLO [3,2-ALPHA]AZEPINE DERIVATIVE | Eisai Co., Ltd. (JP) | 1996-07-03 | — | — | EP | disclosed |
| WO-1996011173-A2 | RACEMISATION OF PRECURSORS TO LEVOBUPIVACAINE AND ANALOGUES THEREOF | CHIROSCIENCE LIMITED (GB) | 1996-04-18 | — | — | WO | disclosed |
| WO-1995010604-A1 | ENZYME AND ITS USE IN PREPARING (S)-PIPECOLIC ACID | CHIROSCIENCE LIMITED (GB) | 1995-04-20 | — | — | WO | disclosed |
| CN-1076928-A | 1-[2-arylsulfonyl amino)-and the 1-oxoethyl] piperidine derivative and preparation and the application in treatment | SYNTHELABO (FR) | 1993-10-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144849-A1 | COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF | CEP170, PIN1, FKBP3 | SMN1; SMN2 4805/4885CYP3A4 2870/4885CYP2D6 3819/4885 |
| US-11987590-B2 | Compounds that participate in cooperative binding and uses thereof | CEP170, PIN1, FKBP3 | SMN1; SMN2 4805/4885CYP3A4 2870/4885CYP2D6 3819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.