Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27594301 | 0.82 | LOXL2 (0.55) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL7212101 | 0.81 | LOXL2 (0.58) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL8591170 | 0.78 | LOXL2 (0.50) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL7152163 | 0.78 | LOXL2 (0.58) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL28879947 | 0.78 | LOXL2 (0.58) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL4810603 | 0.78 | LOXL2 (0.58) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL3397178 | 0.78 | LOXL2 (0.58) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL3817375 | 0.75 | LOXL2 (0.64) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL9572807 | 0.75 | LOXL2 (0.64) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL334360 | 0.72 | LOXL2 (0.67) | LOXL2NCF1HTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39836-E1 | Macrolide antinfective agents | KOSAN BIOSCIENCES, INC. (US) | 2007-09-11 | — | — | US | claimed |
| US-6593302-B2 | Antibiotics | KOSAN BIOSCIENCES, INC. | 2003-07-15 | — | — | US | claimed |