Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7627062 | 0.95 | TSHR (0.83) | TSHRHPGDCYP3A4ALDH1A1TDP1 | |
| SCHEMBL6600454 | 0.95 | TSHR (0.83) | TSHRHPGDCYP3A4ALDH1A1TDP1 | |
| SCHEMBL3401565 | 0.95 | TSHR (0.83) | TSHRHPGDCYP3A4ALDH1A1TDP1 | |
| SCHEMBL7958163 | 0.95 | TSHR (0.83) | TSHRHPGDCYP3A4ALDH1A1TDP1 | |
| SCHEMBL8640150 | 0.95 | TSHR (0.83) | TSHRHPGDCYP3A4ALDH1A1TDP1 | |
| SCHEMBL5993716 | 0.95 | TSHR (0.83) | TSHRHPGDCYP3A4ALDH1A1TDP1 | |
| SCHEMBL17139830 | 0.93 | TSHR (0.81) | TSHRHPGDCYP3A4ALDH1A1TDP1 | |
| SCHEMBL8213029 | 0.93 | TSHR (0.85) | TSHRHPGDCYP3A4ALDH1A1TDP1 | |
| SCHEMBL10795771 | 0.92 | TSHR (0.74) | TSHRHPGDCYP3A4ALDH1A1TDP1 | |
| SCHEMBL7578944 | 0.92 | TSHR (0.78) | TSHRHPGDCYP3A4ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250472-B1 | Can be processed into thermoformable acrylic sheet material with variegated non-homogeneous granite appearance and, bathware, comprising a matrix of polymethyl methacrylate having dispersed within it particles of a thermoplastic | LUCITE INTERNATIONAL, INC. (US) | 2007-07-31 | — | — | US | claimed |
| EP-1153081-B1 | ACRYLIC COMPOSITIONS | LUCITE INT INC (US) | 2006-03-29 | — | — | EP | claimed |
| EP-1153081-A4 | ACRYLIC COMPOSITIONS | INEOS ACRYLICS INC (US) | 2002-11-20 | — | — | EP | claimed |
| EP-1153081-A1 | ACRYLIC COMPOSITIONS | ICI Acrylics, Inc. (US) | 2001-11-14 | — | — | EP | claimed |
| WO-2000024825-A1 | ACRYLIC COMPOSITIONS | ICI ACRYLICS, INC. (US) | 2000-05-04 | — | — | WO | claimed |