Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.78 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7627062 | 0.97 | TSHR (0.83) | TSHRHPGDHCAR2CYP3A4ALDH1A1 | |
| SCHEMBL5993716 | 0.97 | TSHR (0.83) | TSHRHPGDHCAR2CYP3A4ALDH1A1 | |
| SCHEMBL6600454 | 0.97 | TSHR (0.83) | TSHRHPGDHCAR2CYP3A4ALDH1A1 | |
| SCHEMBL7958163 | 0.97 | TSHR (0.83) | TSHRHPGDHCAR2CYP3A4ALDH1A1 | |
| SCHEMBL3401565 | 0.97 | TSHR (0.83) | TSHRHPGDHCAR2CYP3A4ALDH1A1 | |
| SCHEMBL8640150 | 0.97 | TSHR (0.83) | TSHRHPGDHCAR2CYP3A4ALDH1A1 | |
| Acetic Acid SCHEMBL6744109 | 0.96 | TSHR (0.72) | TSHRHPGDHCAR2CYP3A4ALDH1A1 | |
| SCHEMBL17139830 | 0.96 | TSHR (0.81) | TSHRHPGDHCAR2CYP3A4ALDH1A1 | |
| SCHEMBL8213029 | 0.96 | TSHR (0.85) | TSHRHPGDHCAR2CYP3A4ALDH1A1 | |
| SCHEMBL5510132 | 0.92 | TSHR (0.74) | TSHRHPGDHCAR2CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002102587-A1 | PRIMER/MEMBRANE BARRIER SYSTEM | W.R. GRACE & CO.-CONN. (US) | 2002-12-27 | — | — | WO | disclosed |
| WO-1997015173-A1 | METHOD FOR RADIATION-INDUCED THERMAL TRANSFER OF RESIST FOR FLEXIBLE PRINTED CIRCUITRY | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-04-24 | — | — | WO | disclosed |