Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5121874 | 0.91 | PTGDR2 (0.41) | PTGDR2MAPTNPSR1LMNAL3MBTL1 | |
| SCHEMBL5121561 | 0.90 | PTGDR2 (0.46) | PTGDR2L3MBTL1TP53MEN1KMT2A | |
| SCHEMBL5119923 | 0.88 | PTGDR2 (0.46) | PTGDR2L3MBTL1TP53MEN1KMT2A | |
| SCHEMBL5107897 | 0.87 | NPSR1 (0.44) | PTGDR2MAPTNPSR1LMNAL3MBTL1 | |
| SCHEMBL5121197 | 0.86 | PTGDR2 (0.40) | PTGDR2MAPTNPSR1LMNATP53 | |
| SCHEMBL5111272 | 0.85 | ALDH1A1 (0.43) | PTGDR2MAPTNPSR1LMNATP53 | |
| SCHEMBL5120798 | 0.85 | PTGDR2 (0.59) | PTGDR2MAPTNPSR1LMNAL3MBTL1 | |
| SCHEMBL5115406 | 0.84 | PTGDR2 (0.40) | PTGDR2MAPTNPSR1LMNAL3MBTL1 | |
| SCHEMBL5114774 | 0.83 | PTGDR2 (0.47) | PTGDR2MAPTNPSR1LMNAL3MBTL1 | |
| SCHEMBL5106845 | 0.83 | PTGDR2 (0.41) | PTGDR2MAPTNPSR1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784182-A1 | 2-SULFANYL-BENZIMIDAZOL-1-YL-ACETIC ACID DERIVATIVES AS CRTH2 ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006021418-A1 | 2-SULFANYL-BENZOIMIDAZOL-1-YL-ACETIC ACID DERIVATIVES AS CRTH2 ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-03-02 | — | — | WO | disclosed |