SCHEMBL5511337

SCHEMBL5511337

COC(=O)NCC1CN(c2ccc3c(c2)CC(=O)N3C)C(=O)O1

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F10 P00742 14/20 0.54
MAOA P21397 4/20 0.51
MAOB P27338 4/20 0.51
LMNA P02545 1/20 0.49
PTGS1 P23219 1/20 0.49
CALML3 P27482 1/20 0.49
SDHA P31040 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5511332 1.00 F10 (0.54) F10MAOAMAOBLMNAPTGS1
SCHEMBL8126416 0.91 F10 (0.53) F10MAOAMAOBLMNAPTGS1
SCHEMBL5120617 0.91 F10 (0.51) F10MAOAMAOBLMNAPTGS1
SCHEMBL5120610 0.91 F10 (0.51) F10MAOAMAOBLMNAPTGS1
SCHEMBL5111175 0.90 MAOA (0.62) F10MAOAMAOBLMNAPTGS1
SCHEMBL5111177 0.90 MAOA (0.62) F10MAOAMAOBLMNAPTGS1
SCHEMBL5512879 0.89 MAOB (0.47) F10MAOAMAOBLMNAPTGS1
SCHEMBL5512875 0.89 MAOB (0.47) F10MAOAMAOBLMNAPTGS1
SCHEMBL5506553 0.88 MAOB (0.48) F10MAOAMAOBLMNAPTGS1
SCHEMBL5506548 0.88 MAOB (0.48) F10MAOAMAOBLMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1869029-A1 AN OXINDOLE OXAZOLIDINONE AS ANTIBACTERIAL AGENT Pharmacia & Upjohn Company LLC (US) 2007-12-26 EP disclosed
WO-2006106426-A1 AN OXINDOLE OXAZOLIDINONE AS ANTIBACTERIAL AGENT PHARMACIA & UPJOHN COMPANY LLC (US) 2006-10-12 WO disclosed
US-20060229348-A1 Oxindole oxazolidinone as antibacterial agent JOSYULA VARA PRASAD V N 2006-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060229348-A1 Oxindole oxazolidinone as antibacterial agent OXA1L, MRPL21, RPS27L F10 1720/4885MAOA 1789/4885MAOB 1778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.