Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5511508 | 0.79 | ESR1 (0.39) | ESR1ESR2ARAKR1C3KDM4E | |
| SCHEMBL5509895 | 0.77 | ESR1 (0.42) | ESR1ESR2CCNE2CDK4CCND1 | |
| SCHEMBL5515927 | 0.77 | ESR1 (0.40) | ESR1ESR2CCNE2CDK4CCND1 | |
| SCHEMBL5514229 | 0.76 | AR (0.35) | ESR1ESR2ARAKR1C3CCNE2 | |
| SCHEMBL5512648 | 0.74 | KIF11 (0.36) | ESR1ESR2KDM4EMEN1MAPT | |
| SCHEMBL5511601 | 0.74 | TNIK (0.41) | ESR1ESR2KIF11 | |
| SCHEMBL30655671 | 0.74 | ESR1 (0.46) | ESR1ESR2ARAKR1C3KDM4E | |
| SCHEMBL5517850 | 0.72 | ESR1 (0.44) | ESR1ESR2ARAKR1C3KDM4E | |
| SCHEMBL5511735 | 0.72 | ESR1 (0.36) | ESR1ESR2KDM4E | |
| SCHEMBL5513342 | 0.71 | TAAR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208559-B2 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2007-04-24 | — | — | US | disclosed |
| US-20060135712-A1 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2006-06-22 | — | — | US | disclosed |