SCHEMBL5511645

SCHEMBL5511645

Oc1ccc(NC(F)(F)F)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5511735 0.86 ESR1 (0.36) IDO1
SCHEMBL5514103 0.81 ADRB1 (0.36) MEN1KMT2A
SCHEMBL5511476 0.78
SCHEMBL5511545 0.76 ESR1 (0.35)
SCHEMBL5513683 0.74 TMPRSS4 (0.31) IDO1
SCHEMBL5513279 0.73 IDO1 (0.48) IDO1MEN1KMT2A
SCHEMBL5507975 0.72
SCHEMBL5518501 0.72 RET (0.35)
SCHEMBL5516202 0.72 CA9 (0.41) IDO1MEN1KMT2A
SCHEMBL1512796 0.72 PIM1 (0.41) IDO1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208559-B2 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2007-04-24 US disclosed
US-20060135712-A1 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2006-06-22 US disclosed