Acetone

Acetone

SCHEMBL5511792

CC(C)=O.CC(C)O.ClC(Cl)Cl

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
LMNA P02545 3/20 0.46
TP53 P04637 1/20 0.41
TSHR P16473 4/20 0.36
CA4 P22748 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
THPO P40225 1/20 0.33
FFAR3 O14843 1/20 0.33
LCK P06239 1/20 0.33
FYN P06241 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL10415847 0.89 FFAR3 (0.50) ALDH1A1LMNATP53TSHRCA4
Acetone SCHEMBL48035 0.88
Acetone SCHEMBL11461982 0.88 LMNA (0.60) ALDH1A1LMNATSHRCA4TDP1
Acetone SCHEMBL5756892 0.88 LMNA (0.60) ALDH1A1LMNATSHRCA4TDP1
Acetone SCHEMBL10855260 0.88 LMNA (0.60) ALDH1A1LMNATP53TSHRTDP1
Acetone SCHEMBL9234736 0.88 LMNA (0.60) ALDH1A1LMNATSHRCA4TDP1
Acetone SCHEMBL8505655 0.88 LMNA (0.60) ALDH1A1LMNATP53TSHRTDP1
Acetone SCHEMBL2143494 0.88 LMNA (0.60) ALDH1A1LMNATSHRCA4TDP1
Acetone SCHEMBL10768381 0.88 LMNA (0.60) ALDH1A1LMNATP53TSHRTDP1
Acetone SCHEMBL29098211 0.88 LMNA (0.60) ALDH1A1LMNATP53TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107004696-B Display device and preparation method thereof 广州华睿光电材料有限公司 2020-05-22 CN disclosed
CN-105226184-B Electroluminescent device comprising stable organic radical compound 潘才法 2020-01-14 CN disclosed
CN-105226193-B Electroluminescent device containing fused ring compound and metal organic complex 潘才法 2020-01-14 CN disclosed
CN-104277538-B A kind of includes the composition of stabilizer and its application in organic electronic device 潘才法 2019-08-09 CN disclosed
CN-102916097-B A kind of electroluminescent device 潘才法 2017-08-18 CN disclosed
CN-107004696-A Display device and preparation method thereof 广州华睿光电材料有限公司 2017-08-01 CN disclosed
CN-106257703-A A kind of electroluminescent device including metal nanometer cluster 潘才法 2016-12-28 CN disclosed
US-7241614-B2 Methods for producing polypeptides in Aspergillus mutant cells NOVOZYMES A/S (DK) 2007-07-10 US disclosed
US-20040197854-A1 Methods for modifying the production of a polypeptide NOVOZYMES BIOTECH, INC. 2004-10-07 US disclosed
US-6323002-B1 GENERATING PREFERENTIAL PROTEIN; CULTURE MUTANT CELLS WHICH CODE PREFERENTIAL PROTEIN, EXPRESS PROTEIN, RECOVER PROTEIN NOVOZYMES BIOTECH, INC 2001-11-27 US disclosed
US-5958727-A THIS INVENTION RELATES TO METHODS FOR MODIFYING THE PRODUCTION OF A POLYPEPTIDE BY A CELL. NOVO NORDISK BIOTECH, INC (US) 1999-09-28 US disclosed