SCHEMBL5511950

SCHEMBL5511950

CCc1nc(-c2ccc(C(F)(F)F)cc2)sc1COc1ccc(OC(C)(C)C(=O)O)cc1Br

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 17/20 0.54
PPARA Q07869 17/20 0.54
PPARG P37231 10/20 0.54
FFAR1 O14842 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5515748 0.91 PPARD (0.61) PPARDPPARAPPARGFFAR1
SCHEMBL5510531 0.88 PPARD (0.62) PPARDPPARAPPARGFFAR1
SCHEMBL5513499 0.84 PPARD (0.53) PPARDPPARAPPARGFFAR1
SCHEMBL5512102 0.78 PPARD (0.76) PPARDPPARAPPARGFFAR1
SCHEMBL5510796 0.78 PPARD (0.60) PPARDPPARAPPARGFFAR1
SCHEMBL5516731 0.77 PPARD (0.64) PPARDPPARAPPARGFFAR1
SCHEMBL5510557 0.77 PPARD (0.82) PPARDPPARAPPARGFFAR1
SCHEMBL5513407 0.76 PPARD (0.59) PPARDPPARAPPARGFFAR1
SCHEMBL4830322 0.76 PPARD (0.77) PPARDPPARAPPARGFFAR1
SCHEMBL4519221 0.76 PPARA (0.51) PPARDPPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7259175-B2 Peroxisome proliferator activated receptor modulators ELI LILLY AND COMPANY (US) 2007-08-21 US disclosed
US-7259175-B2 Peroxisome proliferator activated receptor modulators ELI LILLY AND COMPANY (US) 2007-08-21 US disclosed
US-7259175-B2 Peroxisome proliferator activated receptor modulators ELI LILLY AND COMPANY (US) 2007-08-21 US disclosed
US-20060084663-A1 Peroxisome proliferator activated receptor modulators ELI LILLY AND COMPANY, PATENT DIVISION (US) 2006-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060084663-A1 Peroxisome proliferator activated receptor modulators PPARG, PPARA, PPARD PPARD 3/4885PPARA 2/4885PPARG 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.