Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 18/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.52 |
| ▸ | PPARA | Q07869 | 11/20 | 0.47 |
| ▸ | PPARG | P37231 | 9/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509821 | 0.92 | PPARD (0.63) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL5510531 | 0.91 | PPARD (0.62) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL5511950 | 0.84 | PPARD (0.54) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL5512102 | 0.83 | PPARD (0.76) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL5510557 | 0.79 | PPARD (0.82) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL5513407 | 0.78 | PPARD (0.59) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL5516731 | 0.78 | PPARD (0.64) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL5515748 | 0.76 | PPARD (0.61) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL5514539 | 0.76 | PPARD (0.65) | PPARDFFAR1PPARAPPARG | |
| SCHEMBL5526130 | 0.74 | PPARD (0.66) | PPARDFFAR1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259175-B2 | Peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2007-08-21 | — | — | US | disclosed |
| US-20060084663-A1 | Peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY, PATENT DIVISION (US) | 2006-04-20 | — | — | US | disclosed |
| EP-1480642-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003072102-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084663-A1 | Peroxisome proliferator activated receptor modulators | PPARG, PPARA, PPARD | PPARD 3/4885FFAR1 48/4885PPARA 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.