Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5512360 | 1.00 | KCNH2 (0.49) | KCNH2SLC2A1 | |
| SCHEMBL2506902 | 0.80 | KCNH2 (0.39) | KCNH2SLC2A1 | |
| SCHEMBL5256971 | 0.76 | KCNH2 (0.60) | KCNH2SLC2A1 | |
| SCHEMBL5252383 | 0.76 | KCNH2 (0.60) | KCNH2SLC2A1 | |
| SCHEMBL5256973 | 0.76 | KCNH2 (0.60) | KCNH2SLC2A1 | |
| SCHEMBL2504913 | 0.76 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL5525352 | 0.76 | KCNH2 (0.42) | KCNH2 | |
| Hydrochloric Acid SCHEMBL5253585 | 0.76 | KCNH2 (0.59) | KCNH2SLC2A1 | |
| SCHEMBL5266886 | 0.75 | KCNH2 (0.48) | KCNH2SLC2A1 | |
| SCHEMBL3373310 | 0.75 | KCNH2 (0.44) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799676-A2 | NEW BICYCLIC ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006032466-A2 | NEW BICYCLIC ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-03-30 | — | — | WO | disclosed |