Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | F3 | P13726 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4212357 | 1.00 | TDP1 (0.61) | TDP1LMNAGSK3BSMN1; SMN2F3 | |
| 4-Methoxycinnamic Acid SCHEMBL16333598 | 0.95 | THRB (0.62) | TDP1LMNAGSK3BSMN1; SMN2F3 | |
| SCHEMBL8750788 | 0.87 | TDP1 (0.46) | TDP1LMNAGSK3BSMN1; SMN2MAPT | |
| SCHEMBL20010336 | 0.86 | TDP1 (0.68) | TDP1LMNAGSK3BSMN1; SMN2F3 | |
| 2-Ethylhexanoic Acid SCHEMBL5969968 | 0.85 | TDP1 (0.66) | TDP1LMNAGSK3BSMN1; SMN2THRB | |
| SCHEMBL27945826 | 0.84 | TDP1 (0.74) | TDP1LMNAGSK3BSMN1; SMN2F3 | |
| SCHEMBL20475032 | 0.84 | TDP1 (0.74) | TDP1LMNAGSK3BSMN1; SMN2F3 | |
| SCHEMBL14487924 | 0.84 | TDP1 (0.59) | TDP1LMNAGSK3BSMN1; SMN2F3 | |
| SCHEMBL8750789 | 0.84 | TDP1 (0.44) | TDP1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL1660425 | 0.83 | TNFRSF1A (0.60) | TDP1LMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106309421-B | Pharmaceutical composition and cosmetic composition | 沃凯索法株式会社 | 2020-08-25 | — | — | CN | disclosed |
| CN-104136498-B | Novel liquid organopolysiloxanes and use thereof | 道康宁东丽株式会社 | 2017-06-20 | — | — | CN | disclosed |
| CN-104136498-A | Novel liquid organopolysiloxanes and use thereof | DOW CORNING TORAY CO LTD | 2014-11-05 | — | — | CN | disclosed |
| WO-2012010554-A1 | USE OF COMPOUNDS RESULTING FROM A SUGAR POLYOL OR FROM A DEHYDROGENATED SUGAR POLYOL DERIVATIVE AS A UV-SCREENING AGENT; ANTISUN COMPOSITIONS CONTAINING SAME; AND NOVEL COMPOUNDS | L'OREAL (FR) | 2012-01-26 | — | — | WO | disclosed |
| US-7863478-B2 | 1,3-Bis-[3-(4-methoxyphenyl)-2-propenoyloxy]-2-oxopropane; novel alpha-hydroxyketone derivatives as light-protection filters for cosmetic or drug products; used in cosmetic protective coatings; solar radiation; sunscreen agents; aging resistance; wrinkle resistance; food additives; dermatology | MERCK PATENT GMBH (DE) | 2011-01-04 | — | — | US | disclosed |
| US-7863478-B2 | 1,3-Bis-[3-(4-methoxyphenyl)-2-propenoyloxy]-2-oxopropane; novel alpha-hydroxyketone derivatives as light-protection filters for cosmetic or drug products; used in cosmetic protective coatings; solar radiation; sunscreen agents; aging resistance; wrinkle resistance; food additives; dermatology | MERCK PATENT GMBH (DE) | 2011-01-04 | — | — | US | disclosed |
| US-20080038213-A1 | Uv Filters | MERCK PATENT GMBH (DE) | 2008-02-14 | — | — | US | disclosed |
| US-20080038213-A1 | Uv Filters | MERCK PATENT GMBH (DE) | 2008-02-14 | — | — | US | disclosed |
| US-7285294-B2 | Hair growth inhibitors and composition containing same | SHISEIDO COMPANY, LTD. (JP) | 2007-10-23 | — | — | US | disclosed |
| US-20050175576-A1 | Hair growth inhibitors and composition containing same | SHISEIDO CO., LTD. (JP) | 2005-08-11 | — | — | US | disclosed |
| EP-1352637-A1 | HAIR GROWTH INHIBITORS AND COMPOSITIONS CONTAINING THE SAME | SHISEIDO COMPANY LIMITED (JP) | 2003-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080038213-A1 | Uv Filters | ERCC4, ERCC1, ERCC5 | TDP1 1260/4885LMNA 236/4885GSK3B 4403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.