SCHEMBL5513256

SCHEMBL5513256

CNc1cccc2c(O)c(F)c(F)c(F)c12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.39
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
RECQL P46063 2/20 0.32
HSD17B10 Q99714 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
APP P05067 1/20 0.32
THRB P10828 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
CASP1 P29466 1/20 0.32
SNCA P37840 1/20 0.32
USP2 O75604 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
HTT P42858 2/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5507552 0.80 MEN1 (0.33) IDO1MAPTHPGDRECQLHSD17B10
SCHEMBL5509695 0.79 MAPT (0.31) MAPTHPGDRECQLHSD17B10TDP1
SCHEMBL5515857 0.77 IDO1 (0.38) IDO1MAPTHPGDRECQLHSD17B10
SCHEMBL5511582 0.76 IDO1 (0.41) IDO1MAPTHPGDRECQLHSD17B10
SCHEMBL7036777 0.75 MAPT (0.38) MAPTHPGDRECQLHSD17B10TDP1
SCHEMBL5510267 0.75 HPGD (0.54) IDO1MAPTHPGDRECQLHSD17B10
SCHEMBL5511753 0.74 IDO1 (0.42) IDO1MAPTTDP1USP2MEN1
SCHEMBL5514303 0.73 MEN1 (0.36) IDO1MAPTHPGDRECQLHSD17B10
SCHEMBL5513559 0.72 ALDH1A1 (0.41) IDO1MAPTHPGDRECQLHSD17B10
SCHEMBL5507586 0.71 IDO1 (0.52) IDO1MAPTHPGDRECQLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208559-B2 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2007-04-24 US disclosed
US-20060135712-A1 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2006-06-22 US disclosed