SCHEMBL5513611

SCHEMBL5513611

Nc1ccc(N)c(F)c1F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
CYP3A4 P08684 7/20 0.38
ALOX15 P16050 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
TDP1 Q9NUW8 5/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
THRB P10828 2/20 0.37
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL112835 0.87 ALDH1A1 (0.43) ALDH1A1CYP3A4ALOX15SMN1; SMN2CASP1
SCHEMBL13385779 0.87 ALDH1A1 (0.38) ALDH1A1CYP3A4ALOX15SMN1; SMN2CASP1
Hydrochloric Acid SCHEMBL3032172 0.84 ALDH1A1 (0.42) ALDH1A1CYP3A4ALOX15SMN1; SMN2TDP1
Hydrochloric Acid SCHEMBL28916996 0.84 ALDH1A1 (0.42) ALDH1A1CYP3A4ALOX15SMN1; SMN2TDP1
SCHEMBL13070003 0.82 ALDH1A1 (0.39) ALDH1A1CYP3A4ALOX15SMN1; SMN2CASP1
SCHEMBL5511047 0.82 ALDH1A1 (0.39) ALDH1A1CYP3A4ALOX15SMN1; SMN2CASP1
SCHEMBL17649942 0.82 TSHR (0.40) ALDH1A1CYP3A4ALOX15SMN1; SMN2CASP1
SCHEMBL1425839 0.82 CYP3A4 (0.40) ALDH1A1CYP3A4ALOX15SMN1; SMN2CASP1
SCHEMBL441345 0.82 KDM1A (0.43) ALDH1A1MEN1KMT2AMAPTCA12
SCHEMBL219898 0.82 ALDH1A1 (0.35) ALDH1A1CA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111662451-B Transparent polyimide film with low phase retardation effect and preparation method and application thereof 武汉依麦德新材料科技有限责任公司 2023-04-18 CN claimed
CN-120330908-B Para-aramid fiber, para-aramid aerogel fiber and respective preparation methods thereof 江苏新视界先进功能纤维创新中心有限公司 2026-03-17 CN disclosed
US-20250346020-A1 LAMINATE AND DISPLAY KANEKA CORPORATION (JP) 2025-11-13 US disclosed
US-20250320338-A1 TRANSPARENT FILM, HARD COAT FILM, AND DISPLAY KANEKA CORPORATION (JP) 2025-10-16 US disclosed
CN-120330908-A Para-aramid fiber, para-aramid aerogel fiber and respective preparation methods thereof 江苏新视界先进功能纤维创新中心有限公司 2025-07-18 CN disclosed
CN-119948089-A Hard coating film and display 株式会社钟化 2025-05-06 CN disclosed
US-20250109264-A1 FILM, METHOD FOR MANUFACTURING SAME, AND IMAGE DISPLAY DEVICE KANEKA CORPORATION (JP) 2025-04-03 US disclosed
US-12234323-B2 Transparent polyimide film and production method therefor KANEKA CORPORATION (JP) 2025-02-25 US disclosed
US-20240392131-A1 RESIN COMPOSITION, MOLDED BODY, AND FILM KANEKA CORPORATION (JP) 2024-11-28 US disclosed
CN-118974146-A Film, method for producing the same, and image display device 株式会社钟化 2024-11-15 CN disclosed
US-20150011726-A1 DIAMINE, POLYIMIDE, AND POLYIMIDE FILM AND UTILIZATION THEREOF TOHO UNIVERSITY (JP) 2015-01-08 US disclosed
US-8466252-B2 Optical film, optical film manufacturing method, transparent substrate, image display device, and solar cell KANEKA CORPORATION (JP) 2013-06-18 US disclosed
US-20120270999-A1 OPTICAL FILM, OPTICAL FILM MANUFACTURING METHOD, TRANSPARENT SUBSTRATE, IMAGE DISPLAY DEVICE, AND SOLAR CELL KANEKA CORPORATION (JP) 2012-10-25 US disclosed
US-20070161681-A1 ETHER DERIVATIVES USEFUL AS INHIBITORS OF PDE4 ISOZYMES PFIZER INC. (US) 2007-07-12 US disclosed
US-7208559-B2 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2007-04-24 US disclosed
US-20060135712-A1 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2006-06-22 US disclosed
WO-2006030873-A1 POLYAMIDE, FILM, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2006-03-23 WO disclosed
EP-0718666-B1 Liquid crystal-aligning agent JSR CORP (JP) 2003-03-26 EP disclosed
US-5698135-A POLYAMIC ACID OBTAINED FROM REACTION OF DIANHYDRIDE OF SPECIFIED TETRACARBOXYLIC ACID AND OF CYCLOBUTANETETRACARBOXYLIC ACID WITH DIAMINE, OR POLYMER OBTAINED BY IMIDIZING SAID POLYAMIC ACID JAPAN SYNTHETIC RUBBER CO., LTD., A JAPANESE CORPORATION (JP) 1997-12-16 US disclosed
EP-0718666-A1 Liquid crystal-aligning agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070161681-A1 ETHER DERIVATIVES USEFUL AS INHIBITORS OF PDE4 ISOZYMES PDE4A, PDE4B, PDE4D ALDH1A1 424/4885CYP3A4 67/4885ALOX15 992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.