Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5508350 | 0.93 | BRD4 (0.48) | BRD4ALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL3996870 | 0.91 | BRD4 (0.47) | BRD4ALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL5511259 | 0.87 | BRD4 (0.46) | BRD4ALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL5505156 | 0.86 | BRD4 (0.46) | BRD4ALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL3998583 | 0.84 | BRD4 (0.46) | BRD4ALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL5516306 | 0.84 | ALDH1A1 (0.44) | BRD4ALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL5620480 | 0.83 | BRD4 (0.46) | BRD4ALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL5506423 | 0.81 | BRD4 (0.48) | BRD4ALDH1A1SMN1; SMN2MEN1LMNA | |
| SCHEMBL5509086 | 0.81 | BRD4 (0.48) | BRD4ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL27720126 | 0.81 | BRD4 (0.44) | BRD4ALDH1A1SMN1; SMN2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844011-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | Aventis Pharmaceuticals Inc. (US) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006081343-A1 | 2-PHENYL-INDOLES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | AVENTIS PHARMACEUTICALS INC. (US) | 2006-08-03 | — | — | WO | disclosed |