Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | OTUD7B | Q6GQQ9 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL550091 | 1.00 | PDE7A (0.41) | PDE7AHPGDHSD17B10NPSR1TP53 | |
| SCHEMBL2697830 | 1.00 | PDE7A (0.41) | PDE7AHPGDHSD17B10NPSR1TP53 | |
| SCHEMBL2697828 | 1.00 | PDE7A (0.41) | PDE7AHPGDHSD17B10NPSR1TP53 | |
| SCHEMBL550092 | 1.00 | PDE7A (0.41) | PDE7AHPGDHSD17B10NPSR1TP53 | |
| SCHEMBL551435 | 1.00 | PDE7A (0.41) | PDE7AHPGDHSD17B10NPSR1TP53 | |
| SCHEMBL2700878 | 0.92 | PDE7A (0.41) | PDE7AHPGDHSD17B10NPSR1TP53 | |
| SCHEMBL3703664 | 0.92 | PDE7A (0.41) | PDE7AHPGDHSD17B10NPSR1TP53 | |
| SCHEMBL3703666 | 0.92 | PDE7A (0.41) | PDE7AHPGDHSD17B10NPSR1TP53 | |
| SCHEMBL2700876 | 0.92 | PDE7A (0.41) | PDE7AHPGDHSD17B10NPSR1TP53 | |
| SCHEMBL4572364 | 0.91 | ALDH1A1 (0.42) | PDE7AHPGDHSD17B10NPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110581-B2 | Lactam compounds and their use as pharmaceuticals | INCYTE CORPORATION (US) | 2012-02-07 | — | — | US | claimed |