SCHEMBL5514872

SCHEMBL5514872

Cc1ccc(-c2ccc(C)c(C)c2OP(=O)(O)O)cc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SRC P12931 4/20 0.39
INPPL1 O15357 4/20 0.39
INPP5A Q14642 3/20 0.39
AKT1 P31749 1/20 0.39
INPP5B P32019 1/20 0.37
TSHR P16473 2/20 0.36
LMNA P02545 2/20 0.36
CYP3A4 P08684 1/20 0.35
GAA P10253 1/20 0.33
S1PR3 Q99500 2/20 0.33
TDP2 O95551 1/20 0.32
NSD2 O96028 1/20 0.32
HSP90AA1 P07900 1/20 0.32
PAX8 Q06710 1/20 0.32
S1PR1 P21453 1/20 0.32
ADORA3 P0DMS8 1/20 0.31
PTPN5 P54829 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5512636 0.87 SRC (0.43) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL295545 0.87 SRC (0.39) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL10699457 0.80 SRC (0.40) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL28667492 0.78 SRC (0.50) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL752773 0.77 SRC (0.43) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL30986768 0.71 MAPT (0.44) INPPL1INPP5AINPP5BLMNACYP3A4
SCHEMBL5936078 0.71 INPPL1 (0.43) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL343312 0.70 INPPL1 (0.47) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL5075768 0.70 SRC (0.45) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL28480121 0.70 INPPL1 (0.41) SRCINPPL1INPP5AAKT1INPP5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8562873-B2 Flame retarder composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2013-10-22 US disclosed
US-20070040154-A1 Flame retarder composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2007-02-22 US disclosed