SCHEMBL752773

SCHEMBL752773

Cc1ccc(-c2cc(C)c(OP(=O)(O)O)c(C)c2-c2ccc(C)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.43
INPPL1 O15357 8/20 0.38
INPP5A Q14642 5/20 0.36
AKT1 P31749 1/20 0.36
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
INPP5B P32019 2/20 0.34
TSHR P16473 2/20 0.33
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.33
PTPN5 P54829 1/20 0.32
GAA P10253 1/20 0.31
TYMS P04818 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3756440 0.89 SRC (0.41) SRCINPPL1INPP5AAKT1MAOA
SCHEMBL10699457 0.88 SRC (0.40) SRCINPPL1INPP5AAKT1MAOA
SCHEMBL295545 0.80 SRC (0.39) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL9309420 0.78 HSD17B1 (0.40) SRCINPPL1INPP5AMAOAMAOB
SCHEMBL28667492 0.78 SRC (0.50) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL5514872 0.77 SRC (0.39) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL3758503 0.77 MAOA (0.41) SRCINPPL1INPP5AMAOAMAOB
SCHEMBL1681135 0.77 GPR84 (0.40) SRCINPPL1INPP5AAKT1MAOA
SCHEMBL28648034 0.76 SRC (0.42) SRCINPPL1INPP5AAKT1INPP5B
SCHEMBL29764284 0.76 SRC (0.42) SRCINPPL1INPP5AAKT1INPP5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8779085-B2 Modified polyimide and method for producing modified polyimide PI R&D CO., LTD. (JP) 2014-07-15 US disclosed
US-20120097439-A1 MODIFIED POLYIMIDE AND METHOD FOR PRODUCING MODIFIED POLYIMIDE PI R&D CO., LTD. (JP) 2012-04-26 US disclosed
EP-2431400-A2 MODIFIED POLYIMIDE AND METHOD FOR PRODUCING MODIFIED POLYIMIDE PI R & D Co. Ltd (JP) 2012-03-21 EP disclosed