SCHEMBL5514992

SCHEMBL5514992

O=C(O)CNn1cccc1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.39
▸ APEX1 P27695 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ MEN1 O00255 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ ALOX12 P18054 1/20 0.38
▸ RECQL P46063 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ HCAR2 Q8TDS4 1/20 0.37
▸ HDAC4 P56524 1/20 0.35
▸ HDAC1 Q13547 1/20 0.35
▸ HDAC7 Q8WUI4 1/20 0.35
▸ HDAC8 Q9BY41 1/20 0.35
▸ HDAC6 Q9UBN7 1/20 0.35
▸ HDAC9 Q9UKV0 1/20 0.35
▸ HDAC5 Q9UQL6 1/20 0.35
▸ FDPS P14324 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3953209 0.75 NPC1 (0.35) POLBAPEX1TDP1L3MBTL1HCAR2
SCHEMBL3757707 0.75 NPC1 (0.41) POLBAPEX1TDP1L3MBTL1LMNA
SCHEMBL13719988 0.75 POLB (0.42) POLBAPEX1TDP1L3MBTL1MEN1
SCHEMBL4860919 0.72 POLB (0.40) POLBAPEX1TDP1L3MBTL1MEN1
SCHEMBL25423241 0.70 CYP1A2 (0.41) POLBAPEX1TDP1L3MBTL1ALDH1A1
SCHEMBL10007663 0.69 MEN1 (0.50) L3MBTL1MEN1ALDH1A1KMT2AHCAR2
SCHEMBL5519857 0.68 HDAC4 (0.41) POLBAPEX1TDP1L3MBTL1MEN1
SCHEMBL31045218 0.68 KMT2A (0.53) POLBL3MBTL1MEN1LMNAKMT2A
SCHEMBL11547219 0.68 MAOA (0.42) POLBAPEX1TDP1L3MBTL1MEN1
SCHEMBL5516710 0.67 KMT2A (0.68) POLBAPEX1TDP1L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 — — EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 — — US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 — — US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 — — EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 — — WO disclosed
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