Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14494376 | 0.90 | KMT2A (0.55) | KMT2AMEN1SMN1; SMN2TSHRCYP3A4 | |
| SCHEMBL3186166 | 0.83 | TSHR (0.62) | KMT2AMEN1SMN1; SMN2TSHRCYP3A4 | |
| SCHEMBL3186158 | 0.83 | TSHR (0.62) | KMT2AMEN1SMN1; SMN2TSHRCYP3A4 | |
| SCHEMBL3190857 | 0.82 | TSHR (0.58) | KMT2AMEN1TSHRCYP3A4CYP2C19 | |
| SCHEMBL5922918 | 0.82 | TSHR (0.58) | KMT2AMEN1TSHRCYP3A4CYP2C19 | |
| SCHEMBL3199233 | 0.81 | TSHR (0.54) | KMT2AMEN1SMN1; SMN2TSHRCYP3A4 | |
| SCHEMBL3199240 | 0.81 | TSHR (0.54) | KMT2AMEN1SMN1; SMN2TSHRCYP3A4 | |
| SCHEMBL3186891 | 0.80 | TSHR (0.58) | KMT2AMEN1TSHRCYP3A4CYP2C19 | |
| SCHEMBL3186905 | 0.80 | TSHR (0.58) | KMT2AMEN1TSHRCYP3A4CYP2C19 | |
| SCHEMBL13318217 | 0.79 | ALDH1A1 (0.66) | KMT2AMEN1SMN1; SMN2TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230058-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7230058-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7230058-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7157523-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-01-02 | — | — | US | disclosed |
| US-7157523-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-01-02 | — | — | US | disclosed |
| US-7157523-B2 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2007-01-02 | — | — | US | disclosed |
| US-20060189771-A1 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2006-08-24 | — | — | US | disclosed |
| US-20060041092-A1 | Ring-opened polynorbornenes | JSR CORPORATION (JP) | 2006-02-23 | — | — | US | disclosed |
| EP-1561766-A1 | RING-OPENED POLYNORBORNENES | JSR Corporation (JP) | 2005-08-10 | — | — | EP | disclosed |