Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5515809 | 0.80 | ESR1 (0.44) | ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL5511545 | 0.75 | ESR1 (0.35) | ESR1ESR2TRPV1 | |
| SCHEMBL5515927 | 0.75 | ESR1 (0.40) | ESR1ESR2KDM4ETRPV1 | |
| SCHEMBL5514162 | 0.75 | ESR1 (0.52) | ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL5512579 | 0.74 | ESR1 (0.47) | ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL5511735 | 0.74 | ESR1 (0.36) | ESR1ESR2KDM4E | |
| SCHEMBL5514272 | 0.73 | CYP1A2 (0.44) | ESR1ESR2HSD17B1HSD17B2TRPV1 | |
| SCHEMBL5511783 | 0.73 | ESR1 (0.37) | ESR1ESR2 | |
| SCHEMBL5515527 | 0.71 | CA3 (0.33) | ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL5514269 | 0.71 | RET (0.34) | HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208559-B2 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2007-04-24 | — | — | US | disclosed |
| US-20060135712-A1 | Ethylened polymer and molded object obtained therefrom | MITSUI CHEMICALS, INC. (JP) | 2006-06-22 | — | — | US | disclosed |