Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2699630 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EPDE7AHPGD | |
| SCHEMBL550218 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EPDE7AHPGD | |
| SCHEMBL551605 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EPDE7AHPGD | |
| SCHEMBL550219 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EPDE7AHPGD | |
| SCHEMBL2699629 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EPDE7AHPGD | |
| SCHEMBL2697412 | 0.93 | PDE7A (0.39) | ALDH1A1MAPTKDM4EPDE7AHRH3 | |
| SCHEMBL3699640 | 0.93 | PDE7A (0.39) | ALDH1A1MAPTKDM4EPDE7AHRH3 | |
| SCHEMBL3699636 | 0.93 | PDE7A (0.39) | ALDH1A1MAPTKDM4EPDE7AHRH3 | |
| SCHEMBL2697416 | 0.93 | PDE7A (0.39) | ALDH1A1MAPTKDM4EPDE7AHRH3 | |
| SCHEMBL17082096 | 0.91 | PDE7A (0.38) | ALDH1A1MAPTKDM4EPDE7AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110581-B2 | Lactam compounds and their use as pharmaceuticals | INCYTE CORPORATION (US) | 2012-02-07 | — | — | US | claimed |