SCHEMBL5516643

SCHEMBL5516643

CC(Oc1ccccn1)(C(=O)O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
LMNA P02545 2/20 0.41
NAPRT Q6XQN6 1/20 0.41
P4HTM Q9NXG6 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
POLB P06746 1/20 0.41
ALDH1A1 P00352 3/20 0.41
CYP1A2 P05177 1/20 0.41
KDM4E B2RXH2 3/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
KMT2A Q03164 1/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KDM6B O15054 1/20 0.38
KDM4A O75164 1/20 0.38
KDM5C P41229 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3368880 0.86 CNR1 (0.46) TSHRLMNANAPRTP4HTML3MBTL1
SCHEMBL8181044 0.81 PPARG (0.44) TSHRLMNANAPRTP4HTML3MBTL1
SCHEMBL10844188 0.80 TSHR (0.42) TSHRLMNANAPRTP4HTML3MBTL1
SCHEMBL3369844 0.80 TSHR (0.48) TSHRLMNANAPRTP4HTML3MBTL1
SCHEMBL1967963 0.80 TSHR (0.42) TSHRLMNANAPRTP4HTML3MBTL1
SCHEMBL24497189 0.79 LMNA (0.41) TSHRLMNANAPRTP4HTML3MBTL1
SCHEMBL5520187 0.78 TSHR (0.43) TSHRLMNANAPRTP4HTML3MBTL1
SCHEMBL2732179 0.77 KDM4E (0.44) TSHRLMNAP4HTML3MBTL1POLB
SCHEMBL31612410 0.77 KDM4E (0.44) TSHRLMNAP4HTML3MBTL1POLB
SCHEMBL27083576 0.76 TLR7 (0.40) TSHRLMNANAPRTP4HTML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed