Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.60 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL25 | 0.94 | — | — | |
| Bicarbonate SCHEMBL714912 | 0.94 | CA4 (0.67) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL28582066 | 0.94 | CA4 (0.67) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL2121875 | 0.94 | CA4 (0.67) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL551759 | 0.94 | CA4 (0.50) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL1331273 | 0.94 | — | — | |
| Bicarbonate SCHEMBL29061109 | 0.94 | CA4 (0.67) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL1331459 | 0.94 | — | — | |
| Bicarbonate SCHEMBL23849739 | 0.88 | CA4 (0.60) | CA4FAHD1CA1MEN1LDHA | |
| Bicarbonate SCHEMBL17963009 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235169-B2 | Method and apparatus for purging and disinfecting water | OMEGA CO., LTD. (JP) | 2007-06-26 | — | — | US | claimed |
| US-20030141202-A1 | Method and apparatus for purging and disinfecting water | OMEGA CO., LTD. | 2003-07-31 | — | — | US | claimed |
| US-11655163-B2 | Clean water for bathing and medical treatments | WATERDIAM GROUP LLC (US) | 2023-05-23 | — | — | US | disclosed |
| EP-4153340-A1 | CLEAN WATER FOR BATHING AND MEDICAL TREATMENTS | WEO, LLC (US) | 2023-03-29 | — | — | EP | disclosed |
| US-20220371925-A1 | CLEAN WATER FOR BATHING AND MEDICAL TREATMENTS | WATERDIAM GROUP LLC (US) | 2022-11-24 | — | — | US | disclosed |
| US-11420885-B2 | Electrolysis method and device for water | WATERDIAM GROUP LLC (US) | 2022-08-23 | — | — | US | disclosed |
| US-20210403348-A1 | ELECTROLYSIS METHOD AND DEVICE FOR SPAS AND POOLS | WEO, LLC | 2021-12-30 | — | — | US | disclosed |
| WO-2021236693-A1 | CLEAN WATER FOR BATHING AND MEDICAL TREATMENTS | WATERDIAM GROUP LLC (US) | 2021-11-25 | — | — | WO | disclosed |
| US-20210363034-A1 | CLEAN WATER FOR BATHING AND MEDICAL TREATMENTS | WEO, LLC | 2021-11-25 | — | — | US | disclosed |
| EP-3759053-A1 | ELECTROLYSIS METHOD AND DEVICE FOR SPAS AND POOLS | Waterdiam France SAS (FR) | 2021-01-06 | — | — | EP | disclosed |
| US-20200283312-A1 | ELECTROLYSIS METHOD AND DEVICE FOR WATER | WEO, LLC | 2020-09-10 | — | — | US | disclosed |
| EP-2970831-A1 | ENZYME-CONTAINING DETERGENT AND PRESOAK COMPOSITION AND METHODS OF USING | Ecolab USA Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014158490-A1 | ENZYME-CONTAINING DETERGENT AND PRESOAK COMPOSITION AND METHODS OF USING | ECOLAB USA INC. (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20130056364-A1 | METHOD FOR THE BLEACHING OF KITCHENWARE IN A DISHWASHER | BASF SE (DE) | 2013-03-07 | — | — | US | disclosed |
| US-7235169-B2 | Method and apparatus for purging and disinfecting water | OMEGA CO., LTD. (JP) | 2007-06-26 | — | — | US | disclosed |
| US-7235169-B2 | Method and apparatus for purging and disinfecting water | OMEGA CO., LTD. (JP) | 2007-06-26 | — | — | US | disclosed |
| US-20030141202-A1 | Method and apparatus for purging and disinfecting water | OMEGA CO., LTD. | 2003-07-31 | — | — | US | disclosed |
| US-20030141202-A1 | Method and apparatus for purging and disinfecting water | OMEGA CO., LTD. | 2003-07-31 | — | — | US | disclosed |