SCHEMBL5518503

SCHEMBL5518503

NS(=O)(=O)c1cccc(O)c1O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK2 P24941 2/20 0.63
STAT3 P40763 1/20 0.55
CA2 P00918 11/20 0.50
CA1 P00915 10/20 0.50
CA6 P23280 4/20 0.50
HSD17B10 Q99714 2/20 0.50
DBH P09172 2/20 0.50
ADAMTS4 O75173 1/20 0.50
ALDH1A1 P00352 1/20 0.50
EGFR P00533 1/20 0.50
LMNA P02545 1/20 0.50
FYN P06241 1/20 0.50
MMP2 P08253 1/20 0.50
MMP9 P14780 1/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
MMP8 P22894 1/20 0.50
MMP12 P39900 1/20 0.50
RECQL P46063 1/20 0.50
TDP1 Q9NUW8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1345089 0.83 TDP1 (0.52) CDK2STAT3CA2CA1CA6
SCHEMBL1121320 0.82 CA1 (0.61) CDK2STAT3CA2CA1CA6
SCHEMBL9509844 0.82 NR4A1 (0.50) CDK2STAT3CA2CA1CA6
SCHEMBL27755945 0.81 STAT3 (0.56) CDK2STAT3CA2CA1CA6
SCHEMBL10638501 0.81 CDK2 (0.48) CDK2STAT3CA2CA1CA6
SCHEMBL29470806 0.81 CDK2 (0.50) CDK2STAT3CA2CA1CA6
SCHEMBL114040 0.81 CDK2 (0.50) CDK2STAT3CA2CA1CA6
SCHEMBL1685391 0.80 ALDH1A1 (0.52) CDK2STAT3CA2CA1CA6
SCHEMBL6657862 0.80 CA1 (0.55) CDK2STAT3CA2CA1CA6
SCHEMBL4658049 0.80 ALDH1A1 (0.52) CDK2STAT3CA2CA1CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3877493-B1 DETERGENTS AND CLEANING AGENTS HAVING IMPROVED PERFORMANCE HENKEL AG & CO KGAA (DE) 2024-09-11 EP disclosed
EP-3877493-A1 DETERGENTS AND CLEANING AGENTS HAVING IMPROVED PERFORMANCE Henkel AG & Co. KGaA (DE) 2021-09-15 EP disclosed
CN-112245773-A Dilatation balloon catheter for narrow digestive tract lesions 浙江桐轩医疗科技有限公司 2021-01-22 CN disclosed
CN-112089480-A Coronary artery cutting balloon and catheter thereof 浙江桐轩医疗科技有限公司 2020-12-18 CN disclosed
US-8173349-B2 Photosensitive resin composition, polymer compound, method of forming a pattern, and electronic device FUJIFILM CORPORATION (JP) 2012-05-08 US disclosed
US-8173349-B2 Photosensitive resin composition, polymer compound, method of forming a pattern, and electronic device FUJIFILM CORPORATION (JP) 2012-05-08 US disclosed
US-20100080963-A1 PHOTOSENSITIVE RESIN COMPOSITION, POLYMER COMPOUND, METHOD OF FORMING A PATTERN, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-20100080963-A1 PHOTOSENSITIVE RESIN COMPOSITION, POLYMER COMPOUND, METHOD OF FORMING A PATTERN, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
CN-1040062-C Pharmacologically active compounds, methods for the preparing thereof and compositions containing same ORION YHTYMAE OY (FI) 1998-10-07 CN disclosed
US-5446194-A Pharmacologically active catechol derivatives ORION-YHTYMA OY (FI) 1995-08-29 US disclosed
US-5283352-A Transferase inhibitor ORION-YHTYMA OY (FI) 1994-02-01 US disclosed
US-5112861-A Inhibitors of catechol-methyl-transferase enzyme, levodopa ORION-YHTYMA OY (FI) 1992-05-12 US disclosed
US-4963590-A ENZYME INHIBITOR FOR TREATING PARKINSON'S DISEASE ALONG WITH DOPA;POTENTIATION ORION-YHTYMA OY (FI) 1990-10-16 US disclosed
CN-87108011-A New compounds with pharmacological activity, preparation method and related components thereof ORION YHTYMAE OY (FI) 1988-06-08 CN disclosed