Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 6/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5522115 | 0.91 | NAMPT (0.39) | NAMPTCNR1BCL2CYP17A1GPR119 | |
| SCHEMBL4923338 | 0.90 | NAMPT (0.41) | NAMPTBCL2CYP17A1GPR119SLC5A1 | |
| SCHEMBL5524902 | 0.87 | NAMPT (0.48) | NAMPTCNR1BCL2CYP17A1GPR119 | |
| SCHEMBL4932007 | 0.86 | NPC1 (0.41) | NAMPTBCL2CYP17A1GPR119NPC1 | |
| SCHEMBL5525584 | 0.83 | CNR1 (0.41) | CNR1CNR2NPC1RAB9A | |
| SCHEMBL5521796 | 0.82 | CNR1 (0.41) | CNR1CNR2 | |
| SCHEMBL4932361 | 0.82 | CYP1A2 (0.38) | NAMPTBCL2GPR119CFTR | |
| SCHEMBL5519799 | 0.78 | CNR1 (0.49) | NAMPTCNR1BCL2CNR2 | |
| SCHEMBL14270461 | 0.76 | RXFP1 (0.34) | NPC1RAB9A | |
| SCHEMBL4934933 | 0.76 | NAMPT (0.48) | NAMPTCNR1BCL2GPR119CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1698626-A1 | AMIDOPYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | PTGER1, PTGS1, PTGER2 | NAMPT 2905/4885CNR1 76/4885BCL2 3148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.