Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 9/20 | 0.37 |
| ▸ | CNR1 | P21554 | 9/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5518699 | 0.91 | NAMPT (0.42) | NAMPTCNR2CNR1CYP17A1BCL2 | |
| SCHEMBL5519799 | 0.88 | CNR1 (0.49) | NAMPTCNR2CNR1BCL2 | |
| SCHEMBL4923338 | 0.86 | NAMPT (0.41) | NAMPTCYP17A1BCL2SLC5A1GPR119 | |
| SCHEMBL4932007 | 0.84 | NPC1 (0.41) | NAMPTCYP17A1BCL2GPR119 | |
| SCHEMBL5529763 | 0.84 | CNR1 (0.40) | CNR2CNR1 | |
| SCHEMBL4932361 | 0.80 | CYP1A2 (0.38) | NAMPTBCL2CFTRGPR119 | |
| SCHEMBL5524902 | 0.78 | NAMPT (0.48) | NAMPTCNR2CNR1CYP17A1BCL2 | |
| SCHEMBL5527649 | 0.76 | CNR1 (0.49) | NAMPTCNR2CNR1 | |
| SCHEMBL5525584 | 0.74 | CNR1 (0.41) | CNR2CNR1ANO1 | |
| SCHEMBL14270461 | 0.73 | RXFP1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| CN-1902191-A | Amidopyrazole derivative | DAIICHI SEIYAKU CO (JP) | 2007-01-24 | — | — | CN | disclosed |
| EP-1698626-A1 | AMIDOPYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | PTGER1, PTGS1, PTGER2 | NAMPT 2905/4885CNR2 43/4885CNR1 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.