Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | CRHBP | P24387 | 2/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25421945 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL453569 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| Oxirane SCHEMBL15638093 | 0.97 | LMNA (0.46) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL3874923 | 0.92 | ITGB2 (0.43) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL17628649 | 0.92 | ITGB2 (0.43) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL22419 | 0.92 | ITGB2 (0.43) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL27671810 | 0.91 | LMNA (0.43) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| Tetrahydrofuran SCHEMBL28823175 | 0.90 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL21436797 | 0.89 | ITGB2 (0.41) | SMN1; SMN2LMNACRHBPCRHR2HTT | |
| SCHEMBL29958439 | 0.89 | ITGB2 (0.41) | SMN1; SMN2LMNACRHBPCRHR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230044-B2 | Intimate physical mixtures containing macrocyclic polyester oligomer and filler | CYCLICS CORPORATION (US) | 2007-06-12 | — | — | US | disclosed |
| US-20060122307-A1 | Intimate physical mixtures containing macrocyclic polyester oligomer and filler | CYCLICS CORPORATION (US) | 2006-06-08 | — | — | US | disclosed |
| WO-2005121233-A1 | INTIMATE PHYSICAL MIXTURES CONTAINING MACROCYCLIC POLYESTER OLIGOMER AND FILLER | CYCLICS CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |
| US-6960626-B2 | Intimate physical mixtures containing macrocyclic polyester oligomer and filler | CYCLICS CORPORATION (US) | 2005-11-01 | — | — | US | disclosed |
| US-20040225058-A1 | Intimate physical mixtures containing macrocyclic polyester oligomer and filler | Goodwin Procter LLP | 2004-11-11 | — | — | US | disclosed |
| US-4113493-A | AMORPHOUS POLYESTER ADHESIVES FOR PHOTOGRAPHIC MATERIALS | EASTMAN KODAK COMPANY (US) | 1978-09-12 | — | — | US | disclosed |