Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5519433 | 1.00 | KCNH2 (0.35) | KCNH2 | |
| SCHEMBL5438244 | 1.00 | KCNH2 (0.35) | KCNH2 | |
| SCHEMBL5439142 | 0.80 | KCNH2 (0.41) | KCNH2 | |
| Hydrochloric Acid SCHEMBL16213418 | 0.79 | KCNH2 (0.38) | KCNH2 | |
| SCHEMBL5261492 | 0.79 | HTT (0.45) | — | |
| SCHEMBL3273358 | 0.79 | BRD4 (0.38) | KCNH2 | |
| SCHEMBL3573905 | 0.78 | KCNH2 (0.38) | KCNH2 | |
| SCHEMBL3581981 | 0.78 | KCNH2 (0.38) | KCNH2 | |
| SCHEMBL5264047 | 0.78 | KCNH2 (0.38) | KCNH2 | |
| SCHEMBL3579608 | 0.78 | KCNH2 (0.38) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799676-A2 | NEW BICYCLIC ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006032466-A2 | NEW BICYCLIC ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-03-30 | — | — | WO | disclosed |