Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 16/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17970284 | 0.89 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL5519429 | 0.80 | KCNH2 (0.35) | KCNH2 | |
| SCHEMBL5438244 | 0.80 | KCNH2 (0.35) | KCNH2 | |
| SCHEMBL5519433 | 0.80 | KCNH2 (0.35) | KCNH2 | |
| SCHEMBL5316143 | 0.79 | PARP1 (0.58) | — | |
| SCHEMBL5262012 | 0.79 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL5262019 | 0.79 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL3273209 | 0.79 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL3576397 | 0.78 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL5263291 | 0.78 | KCNH2 (0.45) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070244103-A1 | Novel Compounds Having an Anti-Bacterial Activity | MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244103-A1 | Novel Compounds Having an Anti-Bacterial Activity | TOP1, TOP2A, TOP2B | KCNH2 3363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.