Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030997 | 0.76 | MAOA (0.41) | — | |
| SCHEMBL226035 | 0.70 | GAA (0.41) | NOX1CYP1A2MAPT | |
| SCHEMBL8272552 | 0.63 | NOX1 (0.44) | NOX1CYP1A2MAPTCYP2C19 | |
| SCHEMBL19244786 | 0.60 | — | — | |
| SCHEMBL31552720 | 0.60 | KMT2A (0.55) | NOX1CYP1A2MAPTCYP2C19 | |
| SCHEMBL8491661 | 0.59 | NOX1 (0.49) | NOX1CYP1A2MAPTCYP2C19 | |
| SCHEMBL4707754 | 0.59 | NOX1 (0.68) | NOX1CYP1A2MAPTCYP2C19 | |
| SCHEMBL9511403 | 0.58 | NOX1 (0.48) | NOX1CYP1A2 | |
| SCHEMBL9508923 | 0.58 | NOX1 (0.48) | NOX1CYP1A2 | |
| SCHEMBL29411773 | 0.58 | NOX1 (0.48) | NOX1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799676-A2 | NEW BICYCLIC ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006032466-A2 | NEW BICYCLIC ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-03-30 | — | — | WO | disclosed |