SCHEMBL5520846

SCHEMBL5520846

CCCC(N)CC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6049902 0.85
SCHEMBL5268021 0.81 S1PR2 (0.48)
Hydrochloric Acid SCHEMBL10815280 0.80 S1PR2 (0.47)
Hydrochloric Acid SCHEMBL2116887 0.80 S1PR2 (0.47)
SCHEMBL4410944 0.78
SCHEMBL27505445 0.77
Formic Acid SCHEMBL29699024 0.76 ALDH1A1 (0.48)
SCHEMBL26688339 0.76
SCHEMBL6809720 0.76
SCHEMBL24126382 0.75 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112538039-B Synthetic method of 3-fluoroindolone compound 福州大学 2022-04-22 CN claimed
CN-112538039-A Synthetic method of 3-fluoroindolone compound 福州大学 2021-03-23 CN claimed
EP-0167919-B1 BENZODIAZEPINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM MERCK & CO. INC. (US) 1993-05-05 EP claimed
US-20220132847-A1 CINNOLINIUM COMPOUNDS FOR USE IN A METHOD OF CONTROLLING UNWANTED PLANT GROWTH SYNGENTA CROP PROTECTION AG (CH) 2022-05-05 US disclosed
CN-112538039-B Synthetic method of 3-fluoroindolone compound 福州大学 2022-04-22 CN disclosed
EP-3956337-A1 HERBICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2022-02-23 EP disclosed
US-20220046923-A1 HERBICIDAL CINNOLINIUM COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-02-17 US disclosed
EP-3924344-A1 CINNOLINIUM COMPOUNDS FOR USE IN A METHOD OF CONTROLLING UNWANTED PLANT GROWTH Syngenta Crop Protection AG (CH) 2021-12-22 EP disclosed
EP-3898594-A1 HERBICIDAL CINNOLINIUM COMPOUNDS Syngenta Crop Protection AG (CH) 2021-10-27 EP disclosed
CN-112538039-A Synthetic method of 3-fluoroindolone compound 福州大学 2021-03-23 CN disclosed
WO-2020212272-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2020-10-22 WO disclosed
EP-0594540-A1 Antiretroviral acyl compounds CIBA-GEIGY AG (CH) 1994-04-27 EP disclosed
EP-0167919-B1 BENZODIAZEPINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM MERCK & CO. INC. (US) 1993-05-05 EP disclosed
US-5175159-A Prevention of premature labor MERCK & CO., INC. (US) 1992-12-29 US disclosed
EP-0421802-A2 3-substituted-1,4-benzodiazepines useful as oxytocin antagonists MERCK & CO. INC. (US) 1991-04-10 EP disclosed
US-5004741-A Cholecystokinin(CCK); Treating Disorders Of The Gastrointestinal Tract, Central Nervous System And Of The Appetite Of Animals MERCK & CO., INC. (US) 1991-04-02 US disclosed
US-4820834-A Benzodiazepine analogs MERCK & CO., INC. (US) 1989-04-11 US disclosed
EP-0284256-A1 Benzodiazepine analogs MERCK & CO. INC. (US) 1988-09-28 EP disclosed
EP-0167919-A2 Benzodiazepine derivatives and pharmaceutical compositions containing them MERCK & CO. INC. (US) 1986-01-15 EP disclosed
EP-0166355-A2 Substituted aminophenyl compounds and acylaminophenyl compounds and pharmaceutical compositions containing them MERCK & CO. INC. (US) 1986-01-02 EP disclosed