Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPEP | Q07075 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5520878 | 1.00 | ENPEP (0.46) | ENPEPALDH1A1CYP2C9L3MBTL1HTT | |
| SCHEMBL7425789 | 0.86 | ENPEP (0.44) | ENPEPALDH1A1L3MBTL1HTTCNR2 | |
| SCHEMBL24372117 | 0.85 | KMT2A (0.40) | ENPEPALDH1A1L3MBTL1HTTKDM4E | |
| SCHEMBL14344719 | 0.85 | ENPEP (0.43) | ENPEPALDH1A1L3MBTL1HTTCNR2 | |
| SCHEMBL4768861 | 0.85 | ENPEP (0.43) | ENPEPALDH1A1CA2CA1 | |
| SCHEMBL4768868 | 0.85 | ENPEP (0.43) | ENPEPALDH1A1CA2CA1 | |
| SCHEMBL20385795 | 0.83 | CYP2C9 (0.43) | ALDH1A1CYP2C9CNR2MEN1KMT2A | |
| SCHEMBL16310594 | 0.83 | CYP2C9 (0.43) | ALDH1A1CYP2C9CNR2MEN1KMT2A | |
| SCHEMBL19933158 | 0.83 | CYP2C9 (0.43) | ALDH1A1CYP2C9CNR2MEN1KMT2A | |
| SCHEMBL17742765 | 0.83 | ENPEP (0.43) | ENPEPALDH1A1L3MBTL1HTTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1741713-A2 | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists | Bristol-Myers Squibb Company (US) | 2007-01-10 | — | — | EP | disclosed |