Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 9/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.51 |
| ▸ | KDM5C | P41229 | 1/20 | 0.51 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.51 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
| ▸ | KDM4A | O75164 | 2/20 | 0.46 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31518306 | 0.93 | KDM4C (0.50) | KDM5AKDM4CKDM5CKDM5BPHF8 | |
| SCHEMBL11912053 | 0.83 | ALDH1A1 (0.53) | KDM5AKDM4CALDH1A1 | |
| SCHEMBL365810 | 0.83 | KDM4C (0.71) | KDM5AKDM4CKDM5CKDM5BPHF8 | |
| SCHEMBL14473377 | 0.83 | KDM4C (0.56) | KDM5AKDM4CKDM5CKDM5BPHF8 | |
| Acetic Acid SCHEMBL6859754 | 0.82 | S1PR2 (0.59) | KDM5AKDM4CKDM5CKDM5BPHF8 | |
| Acetic Acid SCHEMBL9782786 | 0.82 | S1PR2 (0.59) | KDM5AKDM4CKDM5CKDM5BPHF8 | |
| Acetic Acid SCHEMBL18237030 | 0.82 | S1PR2 (0.59) | KDM5AKDM4CKDM5CKDM5BPHF8 | |
| SCHEMBL12602742 | 0.81 | ALDH1A1 (0.50) | KDM5AKDM4CALDH1A1 | |
| SCHEMBL5984578 | 0.81 | KDM4C (0.72) | KDM5AKDM4CKDM5CKDM5BPHF8 | |
| SCHEMBL13791618 | 0.81 | ALDH1A1 (0.56) | KDM5AKDM4CKDM5CKDM5BPHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178712-B2 | Process for the synthesis of Ibandronate sodium | CIPLA LTD. (IN) | 2012-05-15 | — | — | US | disclosed |
| US-4232029-A | 1-Hydroxyimidazole-5-methanamine derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |