Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | RPA1 | P27694 | 2/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | SPR | P35270 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5524300 | 0.88 | CYP11B1 (0.37) | MALT1CCNE1CDK2GSK3B | |
| SCHEMBL5524209 | 0.88 | PIK3CA (0.35) | MALT1RPA1CCNE1CDK2GSK3B | |
| SCHEMBL5520085 | 0.87 | MALT1 (0.37) | MALT1NTRK1RPA1PDE11ACA9 | |
| SCHEMBL5530272 | 0.87 | WDR5 (0.34) | MALT1RPA1 | |
| SCHEMBL5525372 | 0.86 | MALT1 (0.35) | MALT1RPA1CCNE1CDK2GSK3B | |
| SCHEMBL5979134 | 0.86 | NAMPT (0.35) | MALT1RPA1ELANE | |
| SCHEMBL14416571 | 0.86 | RPA1 (0.36) | MALT1RPA1CCNE1CDK2GSK3B | |
| SCHEMBL5517681 | 0.86 | MALT1 (0.35) | MALT1RPA1CCNE1CDK2GSK3B | |
| SCHEMBL5519940 | 0.85 | RPA1 (0.38) | MALT1RPA1 | |
| SCHEMBL5530270 | 0.84 | MALT1 (0.34) | MALT1NTRK1RPA1PDE11A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| CN-1902191-A | Amidopyrazole derivative | DAIICHI SEIYAKU CO (JP) | 2007-01-24 | — | — | CN | disclosed |
| EP-1698626-A1 | AMIDOPYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | PTGER1, PTGS1, PTGER2 | MALT1 3117/4885NTRK1 3841/4885RPA1 1661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.