Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5524758 | 1.00 | HTR4 (0.71) | HTR4DRD2 | |
| SCHEMBL5522502 | 1.00 | HTR4 (0.71) | HTR4DRD2 | |
| SCHEMBL5529804 | 1.00 | HTR4 (0.71) | HTR4DRD2 | |
| SCHEMBL4883983 | 1.00 | HTR4 (0.71) | HTR4DRD2 | |
| SCHEMBL4892940 | 1.00 | HTR4 (0.71) | HTR4DRD2 | |
| Hydrochloric Acid SCHEMBL4887946 | 0.99 | HTR4 (0.70) | HTR4DRD2 | |
| Hydrochloric Acid SCHEMBL4895242 | 0.99 | HTR4 (0.70) | HTR4DRD2 | |
| SCHEMBL4890493 | 0.96 | HTR4 (0.66) | HTR4DRD2 | |
| SCHEMBL4890481 | 0.96 | HTR4 (0.66) | HTR4DRD2 | |
| Hydrochloric Acid SCHEMBL4895192 | 0.95 | HTR4 (0.65) | HTR4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070155780-A1 | Stabilized composition containing 4-amino-5-chloro-n-[(1r, 3r, 5s)-8-methyl-8-azabicyclo[3.2.1]oct-3-y1]-2-[1-methylbut-2-ynyloxy]benzamide | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-07-05 | — | — | US | claimed |
| EP-1736156-A1 | STABILIZED 4-AMINO-5-CHLORO-N-¬(1R,3r,5S)-8-METHYL-8- AZABICYCLO¬3.2.1|OCT-3-YL|-2-¬1-METHYLBUT-2-YNYLOXY|-BENZAMIDE CONTAINING COMPOSITION | Eisai R&D Management Co., Ltd. (JP) | 2006-12-27 | — | — | EP | claimed |
| US-20070155780-A1 | Stabilized composition containing 4-amino-5-chloro-n-[(1r, 3r, 5s)-8-methyl-8-azabicyclo[3.2.1]oct-3-y1]-2-[1-methylbut-2-ynyloxy]benzamide | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-07-05 | — | — | US | disclosed |
| US-20070155780-A1 | Stabilized composition containing 4-amino-5-chloro-n-[(1r, 3r, 5s)-8-methyl-8-azabicyclo[3.2.1]oct-3-y1]-2-[1-methylbut-2-ynyloxy]benzamide | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-07-05 | — | — | US | disclosed |
| EP-1736156-A1 | STABILIZED 4-AMINO-5-CHLORO-N-¬(1R,3r,5S)-8-METHYL-8- AZABICYCLO¬3.2.1|OCT-3-YL|-2-¬1-METHYLBUT-2-YNYLOXY|-BENZAMIDE CONTAINING COMPOSITION | Eisai R&D Management Co., Ltd. (JP) | 2006-12-27 | — | — | EP | disclosed |
| EP-1736156-A1 | STABILIZED 4-AMINO-5-CHLORO-N-¬(1R,3r,5S)-8-METHYL-8- AZABICYCLO¬3.2.1|OCT-3-YL|-2-¬1-METHYLBUT-2-YNYLOXY|-BENZAMIDE CONTAINING COMPOSITION | Eisai R&D Management Co., Ltd. (JP) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005099698-A1 | STABILIZED 4-AMINO-5-CHLORO-N-[(1R,3r,5S)-8-METHYL-8- AZABICYCLO[3.2.1]OCT-3-YL]-2-[1-METHYLBUT-2-YNYLOXY]-BENZAMIDE CONTAINING COMPOSITION | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2005-10-27 | — | — | WO | disclosed |
| WO-2005099698-A1 | STABILIZED 4-AMINO-5-CHLORO-N-[(1R,3r,5S)-8-METHYL-8- AZABICYCLO[3.2.1]OCT-3-YL]-2-[1-METHYLBUT-2-YNYLOXY]-BENZAMIDE CONTAINING COMPOSITION | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2005-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155780-A1 | Stabilized composition containing 4-amino-5-chloro-n-[(1r, 3r, 5s)-8-methyl-8-azabicyclo[3.2.1]oct-3-y1]-2-[1-methylbut-2-ynyloxy]benzamide | AZI2, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, SCN5A | HTR4 278/4885DRD2 941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.