Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29991282 | 1.00 | POLB (0.51) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL1269728 | 0.90 | POLB (0.45) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL11341100 | 0.90 | POLB (0.50) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL4653236 | 0.89 | TDP1 (0.38) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL8150612 | 0.87 | TDP1 (0.54) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL8144161 | 0.87 | POLB (0.46) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL8144949 | 0.87 | POLB (0.46) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL27542648 | 0.84 | HTT (0.36) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL4578717 | 0.83 | POLB (0.48) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL4578579 | 0.82 | POLB (0.50) | POLBAPEX1HTTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7115674-B2 | Dental self-curing resin cement compositions | DENTKIST, INC. (KR) | 2006-10-03 | — | — | US | claimed |
| US-20050049326-A1 | Dental self-curing resin cement compositions | DENTKIST, INC. (KR) | 2005-03-03 | — | — | US | claimed |
| US-7304096-B2 | Highly functional dental adhesive composition | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY AND DENTKIST, INC. (KR) | 2007-12-04 | — | — | US | disclosed |
| US-7115674-B2 | Dental self-curing resin cement compositions | DENTKIST, INC. (KR) | 2006-10-03 | — | — | US | disclosed |
| US-20050277706-A1 | Highly functional dental adhesive composition | KOREAN INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2005-12-15 | — | — | US | disclosed |
| US-20050049326-A1 | Dental self-curing resin cement compositions | DENTKIST, INC. (KR) | 2005-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277706-A1 | Highly functional dental adhesive composition | CD44, HBG2, HBG1 | POLB 234/4885APEX1 1128/4885HTT 911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.