SCHEMBL1269728

SCHEMBL1269728

C=C(C)C(=O)OCCc1c(C(=O)O)ccc(C(=O)O)c1C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.45
APEX1 P27695 1/20 0.45
HTT P42858 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
THRB P10828 1/20 0.42
TSHR P16473 3/20 0.38
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CFD P00746 1/20 0.31
ELANE P08246 1/20 0.31
ALDH1A1 P00352 1/20 0.31
RAD52 P43351 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8150164 0.91 TDP1 (0.49) POLBAPEX1HTTTDP1THRB
SCHEMBL2237265 0.90 POLB (0.42) POLBAPEX1HTTTDP1THRB
SCHEMBL5523401 0.90 POLB (0.51) POLBAPEX1HTTTDP1THRB
SCHEMBL29991282 0.90 POLB (0.51) POLBAPEX1HTTTDP1THRB
SCHEMBL8144939 0.90 POLB (0.42) POLBAPEX1HTTTDP1THRB
SCHEMBL3861873 0.87 POLB (0.40) POLBAPEX1HTTTDP1THRB
SCHEMBL1270061 0.87 THRB (0.44) POLBAPEX1HTTTDP1THRB
SCHEMBL27383301 0.85 POLB (0.45) POLBAPEX1HTTTDP1THRB
SCHEMBL1535476 0.85 TDP1 (0.47) POLBAPEX1HTTTDP1THRB
SCHEMBL16243503 0.84 THRB (0.41) POLBAPEX1HTTTDP1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100098762-A1 Thermosensitive Pluronic Derivative Hydrogels With High Biodegradability And Biocompatibility For Tissue Regeneration And Preparation Method Thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2010-04-22 US claimed
WO-2007064152-A1 INJECTABLE THERMOSENSITIVE PLURONIC HYDROGELS COUPLED WITH BIOACTIVE MATERIALS FOR TISSUE REGENERATION AND PREPARATION MEHTOD THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2007-06-07 WO claimed
US-6858164-B2 Silicone-oil soluble polymer, image display medium using the silicone-oil soluble polymer and image display device using the image display medium RICOH COMPANY LIMITED (JP) 2005-02-22 US claimed
US-6765713-B2 STABLE DISPERSION OF SILICONE OIL SOLUBLE POLYMER AND ORGANIC SULFONIC ACID COMPONENT RICOH COMPANY, LTD. (JP) 2004-07-20 US claimed
US-20030230487-A1 Electrophoretic composition, image display medium using same and image display device TRANSCEND OPTRONICS (YANGZHOU) CO., LTD. (CN) 2003-12-18 US claimed
EP-0425200-A1 Bone cement composition, cured product thereof, implant material and process for the preparation of the same NOBUO NAKABAYASHI (JP) 1991-05-02 EP claimed
CN-118139941-A Adhesive composition 株式会社力森诺科 2024-06-04 CN disclosed
WO-2023068302-A1 ADHESIVE COMPOSITION 株式会社レゾナック 2023-04-27 WO disclosed
CN-108864878-B Method for forming coating film 关西涂料株式会社 2020-10-27 CN disclosed
US-20200231815-A1 RUBBER MODIFIER FOR TIRES HARIMA CHEMICALS, INCORPORATED (JP) 2020-07-23 US disclosed
EP-3666822-A1 MODIFIER FOR TIRE RUBBER Harima Chemicals, Incorporated (JP) 2020-06-17 EP disclosed
CN-110193974-A The manufacturing method of transparent conducting film laminated body and transparent conducting film 日东电工株式会社 2019-09-03 CN disclosed
CN-110197739-A The manufacturing method of transparent conducting film laminated body and transparent conducting film 日东电工株式会社 2019-09-03 CN disclosed
US-6590696-B2 Image display medium and image display device using the image display medium RICOH COMPANY LIMITED (JP) 2003-07-08 US disclosed
US-20030065064-A1 Liquid recording material RESEARCH LABORATORIES OF AUSTRALIA (AU) 2003-04-03 US disclosed
US-20020146572-A1 Silicone-oil soluble polymer, image display medium using the silicone-oil soluble polymer and image display device using the image display medium RICOH COMPANY LIMITED (JP) 2002-10-10 US disclosed
US-20020081515-A1 A liquid recording material containing at least a carrier liquid, a resin, a coloring agent, and a reactive silicone material, an image transfer sheet for use with liquid recording material TSUBUKO KAZUO (JP) 2002-06-27 US disclosed
US-20020027701-A1 Image display medium and image display device using the image display medium RICOH COMPANY LIMITED (JP) 2002-03-07 US disclosed
US-6218465-B1 POLYMERIZING A MONOMER COMPOSITION, MAINLY COMPOSED OF ALKYL (METH)ACRYLATE AND INCLUDING A COMPOUND HAVING A PLURALITY OF POLYMERIC GROUPS WITHIN A MOLECULE, CONTAIN MICROSCOPIC PARTICLES, SUCH AS CARBON BLACK NIPPON SHOKUBAI CO., LTD. (JP) 2001-04-17 US disclosed
EP-0863169-A2 Crosslinked elastomer and producing process thereof NIPPON SHOKUBAI CO., LTD. (JP) 1998-09-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100098762-A1 Thermosensitive Pluronic Derivative Hydrogels With High Biodegradability And Biocompatibility For Tissue Regeneration And Preparation Method Thereof MKI67, CD44, FIBP POLB 3377/4885APEX1 2100/4885HTT 4356/4885
US-20030230487-A1 Electrophoretic composition, image display medium using same and image display device NEFM, ERGIC1, VCL POLB 3273/4885APEX1 3516/4885HTT 1956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.