Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 7/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CHD1L | Q86WJ1 | 1/20 | 0.32 |
| ▸ | PARP9 | Q8IXQ6 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5523568 | 0.94 | GAA (0.37) | POLBGAAMEN1KMT2ANPSR1 | |
| SCHEMBL5520500 | 0.86 | POLB (0.35) | KDM4EALDH1A1SMN1; SMN2POLBTDP1 | |
| SCHEMBL2380769 | 0.82 | ACE (0.38) | KDM4EALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL5518257 | 0.80 | ALDH1A1 (0.41) | KDM4EALDH1A1SMN1; SMN2POLBTDP1 | |
| SCHEMBL5520502 | 0.79 | GAA (0.34) | POLBGAAMEN1KMT2ANPSR1 | |
| SCHEMBL5515711 | 0.79 | ALDH1A1 (0.35) | KDM4EALDH1A1SMN1; SMN2POLBTDP1 | |
| SCHEMBL2380767 | 0.78 | CYP3A4 (0.36) | TDP1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL5530957 | 0.77 | POLB (0.38) | KDM4EALDH1A1SMN1; SMN2POLBTDP1 | |
| SCHEMBL5524057 | 0.74 | POLB (0.40) | KDM4EALDH1A1SMN1; SMN2POLBTDP1 | |
| SCHEMBL5518259 | 0.73 | CYP19A1 (0.40) | KDM4EALDH1A1POLBGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7282601-B2 | Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2007-10-16 | — | — | US | disclosed |
| US-20050038283-A1 | Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester | NEW JAPAN CHEMICAL, CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
| EP-1227078-A1 | DICARBOXYLIC DIESTER, PROCESS FOR PRODUCING THE SAME, AND REFRIGERATING MACHINE LUBRICATING OIL COMPRISING THE ESTER | NEW JAPAN CHEMICAL CO.,LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038283-A1 | Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester | SCO2, PDHX, DECR2 | KDM4E 498/4885ALDH1A1 3078/4885SMN1; SMN2 3160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.