SCHEMBL5523876

SCHEMBL5523876

CCC(C)OC(=O)C1CC=C(C)CC1C(=O)OC(C)CC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
POLB P06746 3/20 0.36
CASP6 P55212 2/20 0.36
CTDSP1 Q9GZU7 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
GAA P10253 2/20 0.35
GRK2 P25098 1/20 0.34
TSHR P16473 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ADORA2B P29275 2/20 0.32
ALDH1A1 P00352 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MAPT P10636 2/20 0.31
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1196613 0.84 POLB (0.43) CA1CA2POLBCASP6CTDSP1
SCHEMBL5526061 0.81 CA1 (0.36) CA1CA2POLBCASP6CTDSP1
SCHEMBL11248916 0.79 CA1 (0.45) CA1CA2POLBCASP6CTDSP1
SCHEMBL1196453 0.79 CA1 (0.45) CA1CA2POLBCASP6CTDSP1
SCHEMBL5512509 0.79 GAA (0.51) POLBGAATSHRCYP1A2CYP3A4
SCHEMBL1196002 0.77 CA1 (0.42) CA1CA2POLBCASP6CTDSP1
SCHEMBL951661 0.76 GAA (0.32) POLBGAATSHRCYP1A2CYP3A4
SCHEMBL1664951 0.75 HCAR2 (0.42) CA1CA2POLBCASP6CTDSP1
SCHEMBL5531100 0.75 POLB (0.45) CA1CA2POLBCASP6CTDSP1
SCHEMBL1196279 0.75 CA1 (0.43) CA1CA2POLBCASP6CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7282601-B2 Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester NEW JAPAN CHEMICAL CO., LTD. (JP) 2007-10-16 US disclosed
EP-1227078-A1 DICARBOXYLIC DIESTER, PROCESS FOR PRODUCING THE SAME, AND REFRIGERATING MACHINE LUBRICATING OIL COMPRISING THE ESTER NEW JAPAN CHEMICAL CO.,LTD. (JP) 2002-07-31 EP disclosed