Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.55 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.55 |
| ▸ | DGAT1 | O75907 | 6/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12392903 | 0.86 | MAPT (0.65) | MAPTSMN1; SMN2CYP1A2LMNACYP2C19 | |
| SCHEMBL4245275 | 0.86 | MAPT (0.58) | MAPTSMN1; SMN2CYP1A2LMNACYP2C19 | |
| Hydrochloric Acid SCHEMBL4243938 | 0.84 | MAPT (0.57) | MAPTSMN1; SMN2CYP1A2LMNACYP2C19 | |
| SCHEMBL2267512 | 0.82 | MAPT (0.64) | MAPTSMN1; SMN2CYP1A2LMNACYP2C19 | |
| SCHEMBL21379546 | 0.81 | MAPT (0.70) | MAPTSMN1; SMN2CYP1A2LMNACYP2C19 | |
| SCHEMBL50482 | 0.80 | MAPT (0.69) | MAPTSMN1; SMN2CYP1A2LMNACYP2C19 | |
| SCHEMBL4500215 | 0.80 | MAPT (0.61) | MAPTSMN1; SMN2CYP1A2LMNACYP2C19 | |
| SCHEMBL6832833 | 0.79 | GAA (0.65) | MAPTSMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL16864479 | 0.77 | MAPT (0.54) | MAPTSMN1; SMN2CYP1A2LMNACYP2C19 | |
| SCHEMBL2790485 | 0.77 | MAPT (0.58) | MAPTSMN1; SMN2CYP1A2LMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101687816-A | Triaminopyrimidine derivatives as the CDC25 inhibitors of phosphatases | IPSEN PHARMA SAS | 2010-03-31 | — | — | CN | claimed |
| CN-101687816-A | Triaminopyrimidine derivatives as the CDC25 inhibitors of phosphatases | IPSEN PHARMA SAS | 2010-03-31 | — | — | CN | disclosed |
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | ARENA PHARMACEUTICALS, INC. | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | MCHR1, GPR119, MCHR2 | MAPT 680/4885SMN1; SMN2 1509/4885CYP1A2 407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.