SCHEMBL5524259

SCHEMBL5524259

O=C(O)c1ccccc1OCCCCCC(C(=O)O)(C(=O)O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
KMT2A Q03164 2/20 0.59
PTK2B Q14289 1/20 0.59
KDM4E B2RXH2 3/20 0.50
HTT P42858 1/20 0.50
LMNA P02545 4/20 0.49
MAPT P10636 2/20 0.49
MEN1 O00255 1/20 0.49
NR1I2 O75469 1/20 0.49
CHRM2 P08172 1/20 0.49
CYP3A4 P08684 1/20 0.49
ADRA2A P08913 1/20 0.49
OPRK1 P41145 1/20 0.49
HTR2B P41595 1/20 0.49
SLC6A3 Q01959 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
PTPN11 Q06124 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
NPC1 O15118 1/20 0.46
CYP2C9 P11712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5513667 0.98 ALDH1A1 (0.61) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL5516789 0.94 ALDH1A1 (0.63) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL5517653 0.89 ALDH1A1 (0.65) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL8926671 0.87 ALDH1A1 (0.76) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL29400029 0.87 ALDH1A1 (0.76) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL571511 0.87 ALDH1A1 (0.76) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL209445 0.84 ALDH1A1 (0.55) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL212173 0.82 ALDH1A1 (0.79) ALDH1A1KMT2APTK2BKDM4EHTT
SCHEMBL28219879 0.81 KMT2A (0.72) ALDH1A1KMT2APTK2BKDM4ELMNA
SCHEMBL28831773 0.81 KMT2A (0.72) ALDH1A1KMT2APTK2BKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed